THE LEGO BATMAN MOVIE 2017, dir. Chris McKay

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THE LEGO BATMAN MOVIE 2017, dir. Chris McKay

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Malignant bone cancer has been diagnosed in a dinosaur for the first time ever
https://sciencespies.com/nature/malignant-bone-cancer-has-been-diagnosed-in-a-dinosaur-for-the-first-time-ever/
Malignant bone cancer has been diagnosed in a dinosaur for the first time ever
A palaeontologist, a medical pathologist, and an orthopaedic surgeon walk into a museum. No, it’s not the start of a joke, but the research team that has now diagnosed the first confirmed case of aggressive bone cancer in a dinosaur.
The specimen in question is a fossilised shin bone from Centrosaurus apertus, a plant-eating horned dinosaur that lived and died roughly 76 million years ago.
What looked – at least on first impression – like a poorly healed fracture turned out to be a tumour engrossing the upper half of the animal’s shin bone, or fibula. The centrosaurus was diagnosed with an osteosarcoma; it’s the most common type of bone cancer in humans, but marks the first confirmed case of any malignant cancer we’ve found in a dinosaur.
“Here, we show the unmistakable signature of advanced bone cancer in [a] 76-million-year-old horned dinosaur – the first of its kind,” said pathologist Mark Crowther. “It’s very exciting.”
The shin bone, with the main tumour mass in yellow. (Danielle Dufault/Royal Ontario Museum/McMaster University)
In humans, osteosarcomas often affect growth-spurting teenagers and young adults. If an osteosarcoma metastasises – grows beyond the bone – it most often spreads to the lungs, but can also form tumours in other bones, and even the brain.
However curious we are about the evolution of diseases such as cancer, soft tissues like tendons, ligaments, bone marrow and tumours, are rarely preserved in fossils. Given a few years – let alone a million – these tissues would decay. So even if dinosaurs were regularly struck down by cancer, any diagnostic samples are going to be hard to find.
Scientists have come across similar cancer-like symptoms on dinosaur fossils before. Unusual lesions in the tail vertebrae of a young hadrosaur resembled a condition called Langerhans cell histiocytosis, a complex cancer which leaves room for debate over its manifestation. In the case of this most recent discovery, the malignancy is far more clear.
The cancer-stricken fossilised shin bone of C. apertus was unearthed in Dinosaur Park Formation in Alberta, Canada back in 1989, and had been stored at the Royal Tyrrell Museum of Palaeontology, outside of Calgary, until its recent reanalysis.
Cross sections of the C. apertus bone were taken first with a CT scanner, the same machine used to identify bone fractures and tumours in people. The X-ray image ‘slices’ were reconstructed to see how the tumour grew through the fossilised bone.
In fact, it had spread through the bone quite extensively, which the team of medical specialists took as a sign that this centrosaur lived with its cancer for quite some time.
Artist’s impression of Centrosaurus apertus. (Royal Ontario Museum/McMaster University)
“This discovery reminds us of the common biological links throughout the animal kingdom and reinforces the theory that osteosarcoma tends to affect bones when and where they are growing most rapidly,” said Seper Ekhtiari, an orthopaedic surgeon-in-training at McMaster University in Toronto, who examined the fossil.
As the cancer was so advanced, the researchers think it might have spread to other parts of the dinosaur’s body, but we don’t have any of those tissue samples – such as the spongy lungs – from this ancient animal to make sure.
“The shin bone shows aggressive cancer at an advanced stage,” said paleontologist David Evans. “The cancer would have had crippling effects on the individual and made it very vulnerable to the formidable tyrannosaur predators of the time.”
After imaging the cancerous shin bone, thin sections were carefully sliced off the fossil and compared to a normal C. apertus fibula, along with one case of human osteosarcoma, from a 19-year-old man who had it in his lower leg.
In their paper, the authors note that ”a similarly advanced osteosarcoma in a human patient, left untreated, would certainly be fatal.”
But they suspect the dinosaur died with its herd mates, possibly in a sudden flood event, because the fossil was found in a massive bed of Centrosaurus bones.
“The fact that this plant-eating dinosaur lived in a large, protective herd may have allowed it to survive longer than it normally would have with such a devastating disease,” Evans said.
And when we often marvel at the age of dinosaurs and their size, big and small, this latest medical discovery brings the plight of the dinosaurs a little closer to home.
“Evidence suggests that malignancies, including bone cancers, are rooted quite deeply in the evolutionary history of organisms,” the authors concluded. Yes, even dinosaurs.
The study is published in medical journal The Lancet Oncology.
#Nature
I don’t think even the Cuban Missile Crisis was this tense.
this scene is extra funny when you realize they’re just… waiting at a cafe to kill time before picking up their kids?
even funnier when you think about these nerds refusing to look at each other through over a decade of cultivator pta meetings
#the absolute cold venom in wangjis expression im dying
#they shouldve come to blows at least once for my entertainment lan zhan wouldve fuckin DECKED jiang cheng
#straight up raw knuckled like bichen who??? whats a guqin idk a cultivation technique just fuckin fisticuffs at dawn
#jiang cheng wouldve been So Thrown Off like how does he even retaliate to lan fuckin wangji rocking his jaw with the good ole fashioned 1-2
#zidian crackling menacingly at his fingertips and wangji just there like i fucking dare you do it pussy
#added bonus if jinling sizhui and jingyi are there to witness
#jinling dramatically outraged but like is he outraged that hanguangjun just backhanded his uncle or
#is he outraged that his uncle is fuckin embarrassing him like can you please step your shit up jiang cheng you have a reputation god damn
#sizhui absolutely slack jawed at the sight of his father going apeshit but he figures you know what imma let him have it…
#jingyi is having the time of his life this is truly the Best Day Ever kick his ASS HANGUANGJUN I GOT YO SWORD FUCK HIM UP
#we’d Love To See It
dude.
i knew a surgeon and he once told me “nobodys insides look like how the textbooks say they will. you never know what you’re going to find in there once you open them up” and that was easily the most ominous thing anyone’s ever said to me

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I was wondering last night if it was at all possible to translate sign language poetry into writing, when translating poetry from one spoken language to another that uses the same communication devices is already a headache. So I found a book about sign language poetry (by Rachel Sutton-Spence) and it is a delightful read! At one point the author describes a poem by Clayton Valli about a boat, in which the rising and falling pattern of the words he chose (which are located at different heights in the signing space) evokes the bobbing motion of a boat on the water as it approaches a bridge. And, okay, it will never be the same thing but you can tinker with written words to create similar effects, like how Victor Hugo’s poem The Djinns uses rising and falling line length to convey quietness then frantic action then a return to stillness.
Then the author analyses a Christmas ASL poem by Dorothy Miles and at first you’re like, this is translatable—she lists things children ask for Christmas, and includes signs like “pets” and “cake” which both involve touching the back of one hand with the other, creating a visual rhyme. The English translation pairs “pets” with “candy cigarettes” to preserve the rhyme. The author adds that symmetry in signed poetry is comparable to assonance: instead of signing ‘2 people walking’ with one hand the poet might sign ‘1 person walking’ with the right hand and ‘1 person walking’ with the left hand, for poetical effect. As English doesn’t have this opportunity for symmetry, you can translate the intent behind this deliberate, aesthetic symmetry as a rhyme. But then the author goes on to describe how Miles uses gentle, fluttering-open ‘5′ handshapes to convey a feeling of magic and excitement, and adds extra finger-wriggling or fluttering to some signs to make them ‘sparkle’, so the poem goes something like magic-shivers-up-arms, magic-run-downstairs, magic-feel-bumps-through-stocking and as a translator, how do you not ruin the specific charm of this poem?? You would have to draw actual sparkles around every verse to convey a similar effect.
I really love poetry for how great it is at making us aware of all the resources and hidden treasures of our own language, that we often overlook in everyday life, but I also love the other side of the coin, how poetry in translation gleefully makes us aware of all the cool things our language lacks.
after corona has been tamed, im going to suck off any doctor or nurse who wants it. idgaf. you saved a bunch of people from rona? you risked your health to help us during a plague? drop em. truly braver than the troops.
First one to make a vaccine gets to smash RAW
Ah.
That’s…uh…very kind of you.
Ah. Hmm.
Could you maybe just donate to Doctors without Borders instead?
The last person you texted, the protagonist of the last TV show you watched, and your icon are now your companions during the zombie apocalypse
Are you gonna survive?
@radpiewhispers , alucard from castlevania, victor and yuuri from yuri on ice… med student, half-vampire and two athletes… most likely yeah
we re too gay to function
I BEG YOUR FUCKING PARDON
It’s true! and you can read all about it on fanlore :)
Siri, show me the worst possible combination of words
Many claim we live in a society, but I posit: do we? Do we really?
Hey, as a heads up for people selling Bi Pride-themed items: this account has suddenly started claiming that they owned the copyright to the bi flag and is asking anyone who sees it being sold to report it back to them. They do not.
Please spread this around. I'd hate to see LGBT+ creators who dont know any better getting scamed into giving these shady people money.

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This kills me every fucking time
thinking about how tesla was in love with a pigeon
he. he what? like, nikola tesla? the one that tried to invent a death ray? that tesla?
yes.
classic lit authors on ao3
Jane Austen: The slowburn writer to end all slowburn writers. Has a mild case of purple prose syndrome. Sets you up to think she’s using a really lame trope or cliche, but then pulls the old BITCH U THOUGHT. Gets in fights with commenters who completely miss the point of her work.
William Shakespeare: Where dick jokes meet feels. Recycles old plots that have been in the fandom for years, but always manages to put a new spin on it. That said, he’s better known for good character writing than good plots. Kind of problematic, but people love him anyway. Laughs at and encourages commenters who completely miss the point of his work.
The Brontë Sisters: Their fics get lots of comments but they never reply. They never leave author notes, either. They share an account, and there are talks of a collab fic coming soon. Write fics for OTPs of questionable healthiness and consent. Only ever write darkfic. Like, REALLY dark. …People are getting kind of worried about them.
Edgar Allan Poe: Also only ever writes darkfic, but at this point, people have moved past being worried about him and have just accepted that he’s weird, he’s morbid, and we love him. Channels his feelings about his ex into his writing. It results in really good stories but everyone’s sort of like, “…Dude.”
Charles Dickens: Trying to set the record for highest wordcount on ao3, and it shows.
Victor Hugo: Currently holds the record for highest wordcount on ao3.
Oscar Wilde: Only ever writes M/M. Has a BAD case of purple prose, but it’s worth it if you manage to get through. His stories are either hilarious or soul-crushing. Or somehow both. People love him but know better than to disagree with him publicly, lest he destroy you with one of his infamous subtweets.
L. Frank Baum: Wrote one really well-loved story that’s among the most famous in the fandom, and it’s literally all he’s known for, and it pisses him off. His popular story became a multichap against his will because it’s the only one of his stories anyone actually reads. He keeps trying to end it so he can work on other things, but always ends up coming back.
Arthur Conan Doyle: Feels L. Frank Baum’s pain. SO much.
James Joyce: Has fascinating ideas, but takes forEVER to get to the point in his stories. Also a stoner, and it shows.
Lousia May Alcott: Writes stories for her unpopular OTP (that’s a NOTP for most of the fandom) and breaks up everyone’s favorite ships, mainly out of spite. Also kills everyone’s favorite characters, less so out of spite.
Mary Shelley: Writes incredible stories, but publishes under her boyfriend’s account because she’s banned from ao3. …Again.
Ah but to be a waterdrop with googly eyes
Calcifer’s cousin
Grandma… It’s me, Anastasia!
I hate you all
gandalf wins for dramatically removing his cape to reveal a second cape.
@blackkatmagic

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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Wheein, enjoying her privacy: hey guys it’s been a little while! I’ve been.. chilling.. look, a new tattoo! Ok cya love you haha
Kim “what is privacy?” Yongsun: LMFAO ok look at me shave my legs on camera haha yall wanna see me get my wisdom teeth removed? Here’s another vlog about my daily life where i show you all the pajamas i own and I will now once again talk about my bowel movements