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Dive into Liver

Here, human liver tissue with and without fibrosis has been reconstructed at cell level in 3D by a combination of fluorescent tagging of cell types tissue clearing, microscopy, and computational software. Insights for understanding liver disease and how to treat it

Read the published research article here

Video from work by Wesley B. Fabyan & Chelsea L. Fortin, and colleagues

Department of Bioengineering, University of Washington, Seattle, WA, USA

Video originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)

Published in Science Advances, February 2026

Off the back of that, they had the idea to do an index of their own based on their own experiences of the cheapest products that many people rely on having increases way above inflation or being removed altogether.

This isn’t just a feeling, Jack literally kept the receipts. They have over 10 years of shopping receipts kept for their food blog.

The twitter thread took off and has now had over 22 million views.

The idea of a separate UK index of everyday products people on lower incomes rley on, that reflects the actual affect of price changes on ordinary people’s finances, has completely taken off and is now being covered in all the major news outlets. It is also being supported by a whole range of organisations, camapaigners, retail industry professionals, data analysts and others.

Jack has put out a call for people in the UK to send their old shopping receipts to add to the exissting data for tracking historic price changes.

Today Jack tweeted that they had permission from the Pratchett estate for the use of the preferred name for the new project: 

See, I LOVE the National Parks. I always have a pass. I got to multiple parks a year. I LOVE them, and always viewed them as this unambiguously GOOD thing. Like, the best thing America has done. 

BUT, I just finished reading this book called “I am the Grand Canyon” all about the native Havasupai people and their fight to gain back their rights to the lands above the canyon rim. Historically, they spent the summer months farming in the canyon, and then the winter months hunter-gathering up above the rim. When their reservation was made though, they lost basically all rights to the rim land (They had limited grazing rights to some of it, but it was renewed year to year and always threatened, and it was a whole thing), leading to a century long fight to get it back. 

And in that book there are a couple of really poignant anecdotes- one man talks about how park rangers would come harass them if they tried to collect pinon nuts too close to park land- worried that they would take too many pinon nuts that the squirrels wanted. Despite the fact that the Havasupai had harvested pinon nuts for thousands and thousands of years without ever…like…starving the squirrels. 

There’s another anecdote of them seeing the park rangers hauling away the bodies of dozens of deer- killed in the park because of overpopulation- while the Havasupai had been banned from hunting. (Making them more and more reliant on government aid just to survive the winter months.) 

They talk about how they would traditionally carve out these natural cisterns above the rim to catch rainwater, and how all the animals benefitted from this, but it was difficult to maintain those cisterns when their “ownership” of the land was so disputed. 

So here you have examples of when people are forcibly separated from their ecosystem and how it hurts both those people and the ecosystem. 

And then when the Havasupai finally got legislation before Congress to give them ownership of the rim land back- their biggest opponent was the Parks system and the Sierra Club. The Sierra Club (a big conservation group here in the US) ran a huge smear campaign against these people on the belief that any humans owning this land other than the park system (which aims at conservation, even while developing for recreation) was unacceptable. 

And it all got me thinking about how, as much as I love the National Parks, there are times when its insistence that nature be left “untouched” (except, ya know, for recreation) can actually harm both the native people who have traditionally been part of those ecosystems AND potentially the ecosystems themselves. And I just think there’s a lot of nuance there about recognizing that there are ways for us to be in balance with nature, and that our environmentalism should respect that and push for sustainability over preserving “pristine” human-less landscapes. Removing ourselves from nature isn’t the answer. 

Oh, how quickly the past is forgotten. 

They are part of the reason A03 is a thing now. Not the whole reason, but part of it. 

The Great Purges of 2002 and 2012 are when ff.net got a wild hair up their ass about THINK OF THE CHILDREN and nuked any fic posted on there that was explicit. Thousands upon thousands of nc-17 smutfics were lost.

Is there any way to spread this info? 

THE OTW WAS CREATED BY FANS SO WE’D HAVE AN ARCHIVE THAT WASN’T SUBJECT TO CORPORATE REVIEW. 

Nonprofit, so that nobody could ever say, “this isn’t making enough money; it’s getting shut down.” (See: Geocities, Quizilla, Figment, G+.) With lawyers involved and a firm awareness of the legalities of fanfic, so nobody would decide “we’ve gotten a nasty letter from a megacorporation with lawyers, so we’re hiding because we can’t afford to face a lawsuit. (Jedi Hurtaholics, Trevizo’s Millennium site.) With teams, so that an argument between co-mods didn’t result in the destruction of a whole archive. (Gryffindor Tower, Detention.)

AO3 IS OUR SITE.

It is by fans, for fans. Fans do all the coding. All the legal paperwork. All the abuse/tos violation complaints. Fans make all the choices about policies. Fans decide how to run the fundraisers. Fans write the blog posts. All the volunteer staff are fans; all the people who train them are fans. Fans wrangle all the tags. 

(And the other OTW projects, too. Fans manage the entries at Fanlore. Fans run the Open Doors project. Fans publish Transformative Works and Cultures.)

EVERYONE WORKING FOR THE OTW LOVES FANDOM. Wants it to survive. Wants it to be awesome for everyone.

(Knows that it can’t be awesome for everyone; some approaches to fandom just clash hard. But they strive to minimize those clashes as much as possible, because they love fandom.) 

AO3 is not some company that decided, “we’ll make a site for fanfic and then…” I don’t know what people are thinking is the reason. Money? Data harvesting? Tax shelter? Amusement and pity?

Nope; AO3 was fans saying, “Livejournal sucks; we’re tired of this fucked-up ‘rebuild every three years’ garbage; WE NEED TO OWN THE DAMN SERVERS.”

You know how we joke that our memes must be completely incomprehensible to outsiders? That’s what’s happening here

But instead of referencing, say, the bone stealing witch or the wonderbread guy or Skyrim or loss.jpeg, classic literature assumes you’re gonna know all the stuff a Back-Then Reader would have known

No kidding, like. when you read Classic Literature™ in context of academia? We’d always get at least a week-long crash-course on the relevant historical context, social tensions, religious understandings, pop-science misconceptions, common literary tropes — And we’d get handed a selection of short stories and poems from other contemporary authors for a sense of the General Cultural Vibe — THEN we would finally read the book.

I mean, imagine trying to understand Stranger Things except you have to guess what all the Star Wars and D&D talk is about based on a single preserved reylo fic and a historical summary of the Satanic Panic. That would be really weird and confusing, right?

So if you’re reading classic lit on your own, without a passionate expert scribbling on the whiteboard to explain ancient memes and break down ye olde Discourse for you? Of course it’s gonna be hard to understand!

It’s natural to struggle, and it’s okay if that’s not your idea of fun.

Also: You don’t have to understand every single reference for the story to work, as long as you get the gist of it. For instance, I haven’t read any of the Gothic novels Jane Austen parodies in Northanger Abbey, but I don’t have to. All I have to understand is, “A fangirl has been reading tons of paranormal romance and dreaming up so much fic in her head that she’s completely unprepared for what real relationships are like.” This should be familiar to absolutely ANYONE on Tumblr. 

“Goodbyes are inherently sad. They mean that something is ending. And this one is specially sad because what we had was so great. But, it’s not all sad, right? We’re moving on to things that we love and we’ll always have the memories of our times together”.