Link to my Ko-Fi

apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.

dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!

although his research was focused on cats, it's already being used to develop drugs for humans too!

on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.

furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.

annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D

As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%

No, no, and NO.

AO3 does not live in “the cloud” because that is other people’s computers, and other people’s computers are vulnerable to censorship.

AO3 is on its own computers. It does still have to be housed somewhere, and I suppose a determined enough hater could try to find that place and go after it, but it’s a lot harder than sending spurious complaints to Amazon or whomever going “BadWrong things are hosted on your cloud service!”

AO3 is not “in the cloud.” AO3 is stored on physical machines that the OTW owns.

Because AI.

To paraphrase a comment on a Gamers Nexus video, the reason computer parts are getting so expensive is that a huge amount of RAM and storage that have not been produced yet were purchased with non-existent money to put in gpus and computers that have also not yet been produced to put in data centers that have not yet been built, to be powered by infrastructure that may never appear, to satisfy demand that does not actually exist, to obtain profit that is mathematically impossible.

So that’s fun. But it means that already owning computers that actually do the thing is SO MUCH BETTER than hiring other people to build more capacity to buy more computers to do the thing.

How bad is the RAM crisis? The price of ddr3, which is like 10-15yo tech, is going up. The price of DDR5 is now stupid expensive, 4+ times as expensive as it was a few months ago.

Mostly because there’s only one company in the world that is capable of generating the kind of chips needed and everyone uses that company because the modern world is a very precarious house of cards held together by tissue and string and we have a 50 foot toddler playing Godzilla with international trade.

Writing 和風細雨 (he2feng1xi4yu3; gentle breeze and light rain) with a cat's tail on a water-writing mat.

Water-writing mats turn black when wet and return to their original colour once dry, so they are often used to practise calligraphy with water. The black colour allows you to see your writing clearly, and the mat can be reused as soon as the writing dries and disappears.