Em, As Per Usual

This one hurt, her work had such a profound effect on my life, thoughts, and politics.

May her memory be a blessing

apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.

dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!

although his research was focused on cats, it's already being used to develop drugs for humans too!

on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.

furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.

annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D

As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%

When I turned 17, we ordered a cake at the grocery store for my party, as we’d done many times before. If you wanted something written on the cake you’d write it into a section of the order form. We requested, very simply, “Happy Birthday Courtney”. When we went to pick it up the day of the party, this is what we got.

The bakery employees had absolutely no explanation for this. The order form, attached to the box, very clearly did not contain any of those extra names. Whomever had done the writing was no longer in, so there was no one to ask how this had happened. The fact that the name ‘Juan’ is misspelled bewilders me to this day. (I’ve never seen ‘Miley’ without the E, either, but it’s believable that someone might spell it that way.) Did this cake slip in from an alternate universe where I’m one quarter of a set of Hispanic quadruplets? Dyslexic Hispanic quadruplets, maybe?

This cake became the focal point of my party. At least two of my friends regularly called me ‘Courtney Mily Jaun Pablo’ for years to come. My siblings and I still reference it sometimes, eleven years later. It is probably the funniest thing ever to occur at any birthday celebration of my life, and may well remain so for the rest of my days.

No One Like You

now, it took us a while to realise it meant "(there is) no one like you". at first, we all parsed it as a botched "no one like(s) you"