sorry to anyone who followed me for anything. you're not getting that

blake kathryn

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trying on a metaphor
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@after-the-hall
sorry to anyone who followed me for anything. you're not getting that

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are you guys hearing about this dude working to developing a vaccine for cats that he's hoping would like. theoretically double their lifespans?
turns out i wasn't making that up, his name is Dr. Toru Miyazaki! he also wrote a book called "The Day Cats Live To Be Thirty", so cats are kind of his thing.
apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.
As they age, almost all cats develop kidney disease, from which they eventually die. Just as in humans, kidney disease i
Dr. Toru Miyazaki’s AIM injection for cat kidney disease enters trials in 2025, aiming for a 2027 release. Greycoat Research supports the sc
whoa wait i actually read the articles and it's so much cooler than just that!!
dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!
although his research was focused on cats, it's already being used to develop drugs for humans too!
on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.
furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.
annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D
man just think, not only could our kitties start living longer, healthier lives, but just maybe dialysis will become as rare and obsolete as the iron lung is for people. what a badass Dr. Toru is!
"But I don't want to turn people into dinosaurs. I wanna cure kittie kidneys!"
Update: So they have done clinical trials and have submitted it for approval as of april 2026. They are expecting it to be available late 2026/early 2027
The AIM protein drug for feline chronic kidney disease has been submitted for approval in Japan (April 2026). We break down clinical trial d
As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%
New 2026 study: AIM protein boosts cat kidney disease survival from 20% to 80%. Discover how this scientific breakthrough is changing the fu
Our cat Scout is in the early stages of kidney disease. This might be available in time to save her!
Is it acceptable that I do shave my legs only because it’s easier to put lotion on my legs when they aren’t too hairy and I do like the feeling of smooth skin when I finish up with it.
I also only really do it once or twice a month so sometimes I do go out in public with hairy legs.
come on man i'm on my lunch break can't you wait???
My situationship from the last two years was the intimacy coordinator on a theatre show I directed last fall that had many many stabbing/choking scenes with retractable prop knives (which are widely known for being unsafe but everyone in the cast consented) and she stabbed me in front of everyone as an example and it was honestly better than any sex we ever had
thank you for being the reason i will never ever ever delete my account this is exactly what i needed to read today

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we used to get christmas episodes of television. halloween episodes. valentines. we used to get television that felt like part of your life. like it was happening alongside your life. now we mostly get 8 episodes dropping all at once every two years and they don't have time for any of that. i miss characters living alongside us
I know I already made a post to this effect but it's so baffling to me when someone defends the fact that headphone jacks are slowly but surely getting phased out by smartphone manufacturers with some variations of "wireless headphones are more convenient anyway" bc like. If we're talking about convenience what I like about wired headphones is that they conveniently have a single plug that makes the same damn pair of headphones universally compatible with every single audio-output-capable device I own, from my phone and my computer to my fucking gameboy and my casette player, it doesn't get any more convenient than that.
spoke deeply to me.
This has been my main argument against "AI" from the very beginning.
OpenAI scraped the entire web. All of which had been a labor of love from humans. Wikipedia is the backbone of a lot of LLMs, and that was volunteer human labor. They stole it and now they're selling it back to us.
And worse, they're trying to destroy the free sources that they stole from. It's destruction of human knowledge on an unprecedented scale. The burning of the library of Alexandria has nothing on this.

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She literally does not give a damn what that old fool is yelling about
the lion does not concern herself with papa
what they don’t tell you is that it lives inside you until you let it out
Black-Eared Kite Kyoto, Japan
no deeper madness than your own making
me before i get my paycheck: i'm so excited to spend this on essentials and save the rest wisely
me as soon as that direct deposit hits: you know i've always wanted to learn the theremin

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oh man the painting on this drawing is insa- fuck do you mean #minecraft build
the specific build in question btw
I looked up some of the artist's other builds and they're all just absolutely incredible
I ever tell you guys about my ethically dubious radio show back in college? The Mad Dad Hour?
it was an entire radio show built around perpetuating a very simple joke, but it was uniquely powerful in its capacity to prompt the reaction I was looking for.
so my slot was at the tail end of rush hour, and i got a fair number of listeners/callers who were on the way home from the office. And like, I had a lot of callers, who almost all wanted to request songs that really didn’t fit with the aesthetic. I had pitched a power pop show when i got my slot, but the callers were not having it; they invariably wanted classic rock.
this made sense in a way. if you think about the demographics of the people who listened to the radio for music in 2010 instead of their ipods or cds or whatever, you’d expect them to skew older right? accordingly, i quickly realized that almost all of the people who called to request songs were Dads of a Certain Age. It was honestly annoying at first - I’m all for most classic rock, but that wasn’t what the show was supposed to be.
And so one day, when i was feeling particularly annoyed with requests that just didn’t fit thematically, i came up with the joke that rapidly became the only reason I kept the show going. Per station rules, I had to play a certain number of pre-recorded PSAs during my show, and before I cut to one I was supposed to read out the song titles and artists for all the music i had played before the break. So this one day when i had to inform the world before the break that the song they just heard was, per a listener’s request, Hey Jude by the Beatles, I decided to do a goof. I said:
“and finally, that last song you heard was Hey Jude, which was of course written and performed by the Rolling Stones.”
I barely had time to get the ads going before the phone started ringing. See, I had been assuming people would realize i was making an obvious joke by claiming one of the most well-known Beatles tracks was a Stones song, but i had failed to consider that my listeners were mostly 55-70 year old dads who were irritated from a long day in the office.
And when those dads heard me, a millennial woman, get the artist of an extremely well-known beatles song WRONG???!
they HAD to call in to correct my ignorance. never in a polite way either, it was condescending and annoyed or nothing. and like, they were just SO personally insulted by my inaccurate reporting that it took a massive amount of effort for me to avoid cracking up during the call. I had never understood why some people would enjoy trolling random strangers on the internet before, but in that moment, I understood the appeal entirely.
obviously i did it again right before the next commercial break, immediately after playing Don’t Stop Me Now by Queen David Bowie.
the phone immediately began to ring.
“ARE YOU AN IDIOT?” one of the callers began, “DAVID BOWIE???? THAT WAS QUEEN!”
“I thought David Bowie was the lead singer of Queen though?” I replied with as much innocent earnestness as i could conjure.
I could hear an intake of breath as the infuriated boomer on the other end of the line struggled to figure out where to even start.
And thus, the Mad Dad Hour was born.
@eduards-stuff I kept doing the same joke for an hour a week for an entire year, and the dads NEVER caught on. After episode 1 of the new format I started taking the angry dad calls on air, which added another layer of hilarity to the whole concept.
My friends on campus knew that hay I was doing and enjoyed tuning in, but only one actual listener ever figured out what I was doing, and he was literally a random 30 year old guy from the netherlands with access to an early internet connection radio service. He was possibly my only actual fan. I only know about him because he went to the effort of making a skype and paying for international service so he could call in, and while I got a few calls from him, the first remains my favorite:
me: hi there, you’ve got TST-
him: *strained, wheezing dutch laughter*
me: hey, is everything o-
him: pfffHAHAHAAH YOU MAKE THEM SO MAD. THEY THINK SO LITTLE OF YOUUUUUUUU BUT THE MEN ARE THE ONES WHO ARE FOOLISH! HA! HA! HA! YOU HAVE DUPED THEM!
me: sir i do not know you and i have never even seen you but i am in romantic love with you.