#amitriptyline

also to be grateful for my stingray heating pad, thanks buddy

A lot of people consider meds as aids so this blog will as well.

Personally, amitriptyline did a lot for my (Jay's) fibromyalgia pain, too! I will always recommend people talk to their doctor about trying it.

Also, yay for heating pads! They're often underrated!

Folks, I screwed up, big time. Men in black at my domicile.

They said hello and read some old ass bible passage. EVERYONE knows I'm a man of god, this made me suspicious immediately.

Then they started talking about witnesses. This shit had my heart pumping like I was on 150mg of amitriptyline. What kind of fucking witness? An eyewitness?

Needless to say, I wasn't going to take any chances. This Applebee's situation had me fucked up, and I'm not gonna be intimidated by the FBI.

Ran for the kitchen and grabbed a knife. Started running on all fours, through the hallways, into the street, squealing like a pig at Babylon.

1. they can't do anything for me and

2. they have no idea why i have an eye twitch and facial pain.

I’m supposed to take it in the evening before bed, which makes it really difficult to get up in the morning. Drowsiness and feeling tired are one of the most common side effects after all, which is why you’re supposed to take it in the evening in order to bypass most of it (feeling tired means nothing if you're already sleeping).

But because of the morning drowsiness I will sometimes sleep to noon during my days off, and days when I got school I will sometimes just sleep in and take a later train, making me a bit late to my lessons.

But yesterday I had an amazing though, why not take the medication waaaay before I go to bed? So I took it around half past five. Around NINE I was so tired I just went to bed and fell asleep within minutes. I usually only go to bed that early if I’m ridiculously sick. It’s now my day off and it’s not even 12.00 yet, and I’ve already finished one errand and taken a long walk. This feels like a life hack, but with ehm, prescription drugs.

Our best guess is that amitriptyline provides pain relief in about 1 in 4 (25%) more people than does placebo and about 1 in 4 (25%) more people than placebo report having at least one adverse event, which may be troublesome, but probably not serious. We cannot trust either figure based on the information available.

The most important message is that amitriptyline probably does give really good pain relief to some people with neuropathic pain, but only a minority of them; amitriptyline will not work for most people...

Amitriptyline has been a first-line treatment for neuropathic pain for many years. The fact that there is no supportive unbiased evidence for a beneficial effect is disappointing, but has to be balanced against decades of successful treatment in many people with neuropathic pain. There is no good evidence of a lack of effect; rather our concern should be of overestimation of treatment effect. Amitriptyline should continue to be used as part of the treatment of neuropathic pain, but only a minority of people will achieve satisfactory pain relief. Limited information suggests that failure with one antidepressant does not mean failure with all.

Not even the info I was looking for, but sounds about right. 🙄

Based on this  review, there's really not much evidence period. Doubting that much more relevant research has come out since 2015. I haven't been seeing it, if so. And it is an older drug which is already a first-line choice--so, not nearly so much impetus there.

Unfortunately common with treatments for nerve pain, in general: throw some initially off-label drugs with CNS effects at it, and hope something sticks. 😩 (The less said about existing psych meds in general from that angle, the better.)

Which makes this monkeying around even more frustrating, since the pain team at Plague Island Hospital already went through that process--and found a combo that kinda works! 

And, as is pretty standard for antidepressants, it's at least as inadvisable to stop taking this stuff abruptly; it's just that nobody is suspected of maybe enjoying the side effects too much.

they prescribed me amitriptyline for a three month trial. but it's an antidepressant and i react very badly to antidepressants 😬.

the rheumatologist claims that it should relieve all of my symptoms from pain, fatigue, headaches, rapid heart rate, tingling & numbness, neck instability etc. i remain dubious but we'll see i guess.