Title I guess

Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:

Acetaminophen: 1950

Albuterol: 1969 (UK) 1982 (US)

Allopurinol: 1966

Alprazolam: 1981

Amitriptyline: 1961

Amlodipine: 1990

Amoxicilin: 1972

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Apixiban: 2012

Aripiprazole: 2002

Aspirin (first NSAID): 1899

Azidothymidine (first antiviral): 1987

Barbital (first barbiturate): 1903

Bupropion: 1985

Buspirone: 1986

Calcium Carbonate (TUMS): 1930

Captopril (first ACE inhibitor): 1981

Chlordiazepoxide (first benzodiazepine): 1960

Chlorothiazide (first thiazide diuretic): 1957

Chlorpromazine (first antipsychotic): 1952

Cyclobenzeprine: 1977

Diphenhydramine: 1946

Furosemide: 1959

Fluoxetine (first SSRI): 1988

Gabapentin: 1993

Glipizide: 1984

Hydrochlorothiazide: 1959

Ibuprofen: 1969 (UK) 1974 (US)

Insulin: 1923 (though many types of insulins would become available over the next century)

Imipramine (first tricyclic antidepressant): 1959

Iproniazid (first antidepressant (MAOI)): 1952

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Lisinopril: 1987

Lithium: 1949

Losartan (first ARB): 1995

Lovastatin (first statin): 1987

Naproxen: 1976 (Rx) 1990 (OTC)

Nitrogen Mustard (first chemotherapy agent): early 1940's

Methotrexate: 1947

Methylphenidate: 1954

Metformin: 1957 (France) 1995 (US)

Metoprolol: 1978

Montelukast: 1998

Morphine: early 1800's

Omeprazole: 1989

Penicillin: 1945

Phenbezamine (first antihistamine): 1942

Prednisone: 1955

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Sertraline: 1990

Spironolactone: 1959

Sulfanilamide (first modern antibiotic): 1935

Tolbutamide (first oral anti-diabetic drug): 1956

Tramadol: 1977 (Germany) 1995 (US)

Trazodone: 1981

Valacyclovir: 1995

Verapamil (first calcium channel blocker): 1964

Warfarin: 1954

Morphine: early 1800's

Aspirin (first NSAID): 1899

Barbital (first barbiturate): 1903

Insulin: 1923 (though many types of insulins would become available over the next century)

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Calcium Carbonate (TUMS): 1930

Sulfanilamide (first modern antibiotic): 1935

Nitrogen Mustard (first chemotherapy agent): early 1940's

Phenbezamine (first antihistamine): 1942

Penicillin: 1945

Diphenhydramine: 1946

Methotrexate: 1947

Lithium: 1949

Acetaminophen: 1950

Chlorpromazine (first antipsychotic): 1952

Iproniazid (first antidepressant (MAOI)): 1952

Methylphenidate: 1954

Warfarin: 1954

Prednisone: 1955

Tolbutamide (first oral anti-diabetic drug): 1956

Chlorothiazide (first thiazide diuretic): 1957

Metformin: 1957 (France) 1995 (US)

Furosemide: 1959

Hydrochlorothiazide: 1959

Spironolactone: 1959

Imipramine (first tricyclic antidepressant): 1959

Chlordiazepoxide (first benzodiazepine): 1960

Amitriptyline: 1961

Verapamil (first calcium channel blocker): 1964

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Allopurinol: 1966

Albuterol: 1969 (UK) 1982 (US)

Ibuprofen: 1969 (UK) 1974 (US)

Amoxicilin: 1972

Naproxen: 1976 (Rx) 1990 (OTC)

Cyclobenzeprine: 1977

Tramadol: 1977 (Germany) 1995 (US)

Metoprolol: 1978

Captopril (first ACE inhibitor): 1981

Trazodone: 1981

Alprazolam: 1981

Glipizide: 1984

Bupropion: 1985

Buspirone: 1986

Zopiclone (first "Z-drug"): 1986

Lovastatin (first statin): 1987

Azidothymidine (first antiviral): 1987

Lisinopril: 1987

Fluoxetine (first SSRI): 1988

Omeprazole: 1989

Amlodipine: 1990

Sertraline: 1990

Gabapentin: 1993

Losartan (first ARB): 1995

Valacyclovir: 1995

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Montelukast: 1998

Aripiprazole: 2002

are we the baddies: SFF subgenre focused on agents of an imperial power realizing that and grappling with what to do next, in contrast to stories focusing on the scrappy rebels resisting said imperial power

I could fix him (the empire): SFF subgenre where the colonized subject being nice and/or sexy enough Ends Colonialism, frequently tied to the John President of Racism problem

librarian bait: books centered on the transformative life-changing power of books and libraries, cousin to books focused on the transformative life-changing power of storytelling and narrative in general

college brochure fiction: stories where the protagonist has an artfully arranged group of diverse friends who are as flat as paper and whose cultural backgrounds never come up meaningfully

It hails from an immortal tumblr post by penultimate-step, except not immortal apparently because I get 'not found' when I try to go back to the original. (Edit: Link found) So here's the text:

Gunshots: $100

Poisonings: $200

👎 Kids (Teens are fine tho)

👎 Bystanders

👎 Other Hitmen

First Person - $450, additional bodies add $375 each

(Basically a steal still my normal rate is $650. Cmon guys it’s $200 off!)

See, every time we see the streets of central (at least in the anime, I don't know about the manga rn) there's almost no cars or traffic to be seen. This leads me to believe that there's way fewer cars in Central than we'd assume (I mean, this is a major city in the 1914, a car might be too expensive/not pay off), but that does not explain how all of these citizens actually get around since we also *never* see anyone take any public transportation. They do have tunnels under central (Pride's abode), but I doubt they have an actual subway, and a tram would make a lot of sense, but we never actually*see* one, and Ed and Al always walk everywhere.

I doubt it, but maybe they have a Barcelona-mega-blocks thing going on, with only the major roads actually drivable, and a lot of side streets being pedestrian first/walkable zones? (there do seem to be a lot of dark and dank alleyways in Central tho).

the op linked the study in the replies & i’ve been skimming it & it’s actually rlly rlly interesting to think abt

in the appendix (which you can find by scrolling down) CA:TWS is listed as having one torture scene, which immediately made me wonder because there are two that I can think of.

further on in the appendix when the authors are discussing the criteria for including torture, they give the vault scene in CA:TWS as an example of a scene that isn't torture, with the justification that Bucky seems to comply with his captors, and given the information shown on screen we can't conclude whether or not Bucky is a willing participant in the "wipe." Willing participants cannot be tortured, therefore the vault scene is not counted as torture

That is a WILD take on that scene. "doesn't fight back" does not equal "not being tortured" come on now

now, I could see disqualifying the vault scene as being a torture scene on the basis that the purpose of the "wipe" is not to inflict pain, it just happens to be an extremely painful process.

That's an interesting take. Is doing something incredibly painful or distressing to a person torture when there is ostensibly a secondary purpose to the painful thing, even though it also clearly doubles as a way of inflicting suffering and asserting power? This is a really important question to answer, since a lot of instances of torture and mistreatment in prisons and military situations etc. seem to fall under this. e.g. a strip search is nominally for "security" purposes, but it is also forced nudity which is a common form of sexual violence inflicted as part of torture.

But disqualifying the scene because there is not enough evidence that Bucky is being coerced to do it is nuts, since immediately prior Bucky gets slapped in the face for not answering a question and doesn't retaliate, and immediately before that Bucky gets a bunch of guns pointed at him when he acts up

That's another important question. Does being forced to comply with or participate in your own torture disqualify it from being torture?

The answer is, to me, obviously no, and in fact this seems like a relatively common feature of torture: e.g. forcing prisoners to dig their own graves requires a good amount of compliance from the victim and that's a major reason why it's so distressing