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hello vonnie
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blake kathryn
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Today's Document
sheepfilms
we're not kids anymore.
Jules of Nature
Cosmic Funnies

ellievsbear

oozey mess
Aqua Utopia|海の底で記憶を紡ぐ

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YOU ARE THE REASON

titsay
d e v o n

Andulka
will byers stan first human second

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@tinkadreamchaser

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been meaning to draw them as this peanuts comic for a minute now. i asked my friend rocky he said 🎵❗️
Will and Winston reunite
hey remember when people said we gotta keep talking about this and then two days passed and it just went quiet. anyways
due to recent (and frankly ongoing as far as this website is concerned) events
FTL as textposts
made my day

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For millions of people managing type 2 diabetes, mornings begin the same way — a needle, a dose, and a quiet mental note to do it all again
"For millions of people managing type 2 diabetes, mornings begin the same way — a needle, a dose, and a quiet mental note to do it all again tomorrow.
That routine just changed.
On March 26, 2026, the U.S. Food and Drug Administration approved Awiqli (insulin icodec-abae), developed by Novo Nordisk, as the first and only once-weekly basal insulin ever approved for adults with type 2 diabetes in the United States.
This is not a minor update to an existing drug.
It is the first entirely new class of basal insulin to reach U.S. patients in more than two decades.
Instead of injecting insulin every single day, people with type 2 diabetes using Awiqli will only need one shot per week, on the same day, every week.
That means reducing from 365 injections a year down to just 52.
For anyone who has ever felt the weight of that daily ritual — the anxiety of forgetting, the physical discomfort, the constant reminder that their body needs help — this approval represents something much bigger than a dosing schedule.
It represents relief.
How the Drug Actually Works
Understanding why this injection lasts a full week requires a quick look inside the body.
Most traditional basal insulins are absorbed into the bloodstream and begin breaking down within 24 hours, which is why patients need a fresh dose every day to maintain stable blood sugar levels.
Awiqli works differently.
Its active ingredient, insulin icodec-abae, is engineered to loosely attach to a blood protein called albumin, which is found naturally and abundantly in the bloodstream.
This attachment creates a slow-release reservoir.
Instead of flooding the system and fading fast, the insulin releases gradually and consistently over an entire seven-day period, keeping blood sugar in a healthy range around the clock...
The FDA reviewed and ultimately declined to approve it for people with type 1 diabetes, citing concerns about a modestly increased risk of hypoglycemia in that population specifically.
Some regulatory agencies in other countries, including the European Union, Canada, Australia, and Japan, have approved Awiqli for both type 1 and type 2 diabetes, but for now the U.S. approval is limited to type 2...
What Comes Next
Awiqli is not standing alone in this space for long.
Eli Lilly is developing its own once-weekly basal insulin, called efsitora alfa, which is currently in late-stage clinical trials.
If that drug also earns FDA approval, it would give patients and doctors two once-weekly options to choose from, allowing for personalized decisions based on a patient’s health profile, insurance coverage, and individual response.
The broader direction of travel in diabetes care is unmistakable.
Fewer injections, smarter formulations, and better integration with digital tools like continuous glucose monitors and insulin-tracking apps are all converging toward a future where managing diabetes requires less daily mental effort without becoming any less medically precise...
A Small Shot With Large Implications
It is easy to look at a once-weekly injection and see only a scheduling change.
But the science behind Awiqli, the scale of the ONWARDS trials, and the consistent satisfaction reported by patients all point toward something that matters far more than convenience.
Diabetes management has always asked a lot of people.
It asks for daily vigilance, daily discipline, and a daily willingness to confront one’s own condition, sometimes in uncomfortable or inconvenient circumstances.
Anything that reduces that load, without reducing the quality of care, is worth taking seriously.
For the more than 37 million Americans living with diabetes, and the hundreds of millions more around the world, a simpler weekly routine could mean the difference between a treatment plan that works on paper and one that actually works in a person’s life.
That is the real significance of what the FDA approved on March 26, 2026.
Not just a new drug.
A new way of keeping people healthy, one week at a time."
-via Science Aim, March 29, 2026.
added the Jax and Pomni one and here's all of them!! 🫶
happy birthday to ib!!
helllooooo sailorrrr
“i also choose this guy’s dead wife” was easily the #1 funniest thing to ever be written on the internet.
you can know the punchline but you can’t stop it from punching you.
i do also feel the need to add that phil8248 really liked the joke. he said his wife had always had a dark sense of humour, even about her illness and death, and seeing the joke made him feel like he was laughing with her one last time.

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skweezy jibbs is a international treasure
Saw this in the comments lol
every time i sit down 2 watch a horror movie i think of that one tweet :/
rb if you too sit down in ur room and watch horror movies alone
to anyone in the areas impacted by the wildfire smoke, my #1 biggest piece of advice as someone whos been dealing with wildfire smoke in the NW united states for years, is build yourself a Corsi-Rosenthal Cube
they perform as well as expensive HEPA air cleaners, and are comparatively VERY inexpensive. all you need is a box fan, 4 air filters, a piece of cardboard, and some duct tape!!!!
i think it took us maybe a half hour to put ours together, if that, and we replace the filters every 3 months. it's really made a HUGE difference, both when the air quality is bad, but also with our allergies
Saw these easy to read instructions on Twitter. Stay safe 💚
Great time to start pricing this out by the way, fire season starts… on the summer solstice this year, that’s fun. Signs point to it being a doozy.

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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Hey, did you know archive.org has a bunch of free 90s shows you can stream?
The problem is finding them, since no one's organized them all in one place with covers and episode info. I'm trying to fix that with my new website.
It's in BETA right now, and all the content was just added today, so I've barely scratched the surface of what's out there.
Let me know what you think and what kind of shows/movies you want to see!
http://90sKid.com
We now have a Watch Party with chat feature now live HERE
You can create a live tv channel with our existing library. The channel is time syned so whoever is watching with you will share the moment!
It also works with youtube links and archive.org links.
I actually do think we should discourage women from becoming housewives. Do not become financially dependent on a man. That's how a lot of women ended up dead over the years. A man gets violent suddenly and you have to choose between homelessness or potentially dying at his hand because you have an enormous gap in your resume and no degrees or certifications or anything that will help you pursue a career that will allow you to be financially independent. He owns your bank account. His name is probably the one on the car. Try and leave and he can report it stolen. Where will you go then?
Don't become a housewife.