Make Her A Member of the Midnight Crew

apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.

dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!

although his research was focused on cats, it's already being used to develop drugs for humans too!

on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.

furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.

annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D

As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%

Uber is a fucking shell game of a company designed to leech investor capital and output bootleg cabs.

Nvidia posted a profit in 2023 of $4.37 billion. This is like someone stealing less than a penny from me.

And they lock this kid in a prison hospital for LIFE?

My nephew is very allergic to eggs, peanuts, tree nuts, and sesame. Last year my sister discovered all hot dogs and hamburger buns now contain sesame. Not "may contain", but listed in the ingredients. This year basically every brand of sliced bread also now contains sesame, making it very difficult to find bread items he can eat.

They're just adding it to their products, so they can just list it as an ingredient and not bother with worrying about cross contamination. And they aren't even bothering with telling anyone. Capitalism is going to kill us all.

"Which brings us back to Kellogg’s. Back in 2016, the company found a way around the added burden and expense of complying with the FSMA: they simply began adding trace amounts of peanut flour to their cracker products. Doing so allowed them to list peanuts as an ingredient of the product, freeing them from having to prevent cross-contact.

This is a harm reduction post about DIY

I've seen some people recently using the term "bathtub estrogen" as a little joke about the production of DIY estradiols. This is fine by me as a joking term, I get that people are 1) trying to evoke a DIY punkish or prohibition moonshine sort of image and 2) communicating that we are having to turn to much less carefully prepared forms of medicine than cis people can access when we use DIY. However I recently saw a trans woman with a large platform make the joke and then when asked about it sort of waffle around the topic for a bit and then shruggingly say she does think that some estrogen is made in a bathtub in a way that made it pretty clear she doesn't actually know much about the production side of DIY. She also gestured to a global south DIY producer as being the one who was doing this, which I think is just clumsily labelling people overseas as a bit dumb and less clean.

I've been researching the production of DIY HRT for a few years as I think that the overseas supplies of DIY will be the next thing to be cracked down on by the government after all legally prescribed forms of HRT for trans people are shut down. My aim in researching it is to spread the relevant information to reduce harm for DIY users without making anyone's operations obvious to malicious parties. I can't entirely rule out the possiblity that someone very dumb and reckless is producing DIY in a place that is not sufficiently sterile, and this is part of the inherent risk of DIYing. I can however say that anyone who could afford to get the ingredients to produce DIY estradiols categorically has the money to use a professional-grade lab for it.

I would like to be clear here: bathtub estrogen does not exist

on the other hand...