G-PROTEIN COUPLED RECEPTORS * All eukaryotes have * Act indirectly on a separate protein (enzyme or ion channel) * Trimeric GTP-binding protein (G-protein) mediates this interaction * Same signal molecule can activate multiple different receptors
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G-PROTEIN COUPLED RECEPTORS * All eukaryotes have * Act indirectly on a separate protein (enzyme or ion channel) * Trimeric GTP-binding protein (G-protein) mediates this interaction * Same signal molecule can activate multiple different receptors

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USMLE Step 1 as an IMG
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A sample USMLE Step 1 Study Schedule and Preparation Timetable so detailed, it leaves nothing to chance.
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ELECTRON TRANSPORT CHAIN * Complex I: NADH dehydrogenase - aka NADH-CoQ reductase - NADH delivers 2 electrons to the complex I and is oxidized to NAD+ * CoQ (aka Q10 and ubiquinone) - Lipid-soluble - Mobile carrier - NOT a protein * Complex II: su
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First drawing
Single circular chromosome with inner and outer strands. — In reality, bacterial DNA is arranged in loops. Recall that there is no distinct nucleus, as in eukaryotic cells; instead, DNA lies in the nucleoid region.
Origin of replication is marked by oriC; this is where the replication initiator proteins bind.
Terminus is located opposite oriC; this is the region where DNA replication terminates.
Second drawing After DNA replication begins:
Outer and inner parental strands begin to separate in bidirectional replication.
Replication "bubble," is the space between the strands.
Two y-shaped replication forks, one on each side of the bubble.
DNA helicases separate the parental DNA strands in short segments, thus creating the replication forks; if the two strands separated all at once, excessive DNA damage could occur.
Developing daughter strands: each one begins at the origin of its parental strand and grows towards its terminal end. — These complementary daughter strands are synthesized by the replisome,which comprises DNA polymerase III and other components.
Third drawing
The parental and growing daughter strands are further along in the replication process. — The parental strands have further separated from each other as the daughter strands grow towards the terminal region.
Fourth drawing
Finally, the chromosomes separate after the daughter strands are complete.
DNA replication is semiconservative: — Each new chromosome comprises one strand of DNA from the parental chromosome and one complementary daughter strand.

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Epistasis * Refers to how a gene at one locus affects the expression of a gene located elsewhere. How to create this Punnett Square: * 2 black mice with the same genotype, big B, little b, big C, little C. - Big B is the dominant black allele
Learn about epistasis and punnet squares :)
VASCULAR RESISTANCE
The impediment to blood flow
Total peripheral resistance (aka, systemic vascular resistance)
Describes the resistance to blood flow throughout the entire systemic vasculature (throughout the entire body).
Vascular resistance
Resistance within a single organ; for example, resistance within in the kidney.
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