I'm still thinking about Gwen Stacy in Gotham.
She doesn't have a ton of characterization unfortunately because she's one of the prime example of fridging (and I think her death is important to the Spider-man mythos, totally, but is also a drop in a sea of a larger issue), but there IS also Ghost Spider (Spider Gwen) that we can look at.
Gwen is, much like MJ, someone who complements Peter. She's the scientist side of him. Smart, determined, willing to put herself on the line to help him.
She understands Spider-man.
She's the daughter of a police officer. She had to bury both her parents before she made it to college.
Dying, especially at Peter's hands, would fuck her up majorly. But also she would worry more about what Peter must've felt like, to bury yet another person he loved. Because she understands the feeling. And I don't think she'd regret getting involved. Her dad gave his life to save New York (I'm more referencing the live action film because I do NOT want to deal w detangling more than 60 years of comic books and retcons) and she didn't hesitate to do the same.
When she finds herself in Gotham, she's stuck in the middle of a Joker attack. The whole situation is so reminiscent that she doesn't even compute that she should be dead and that she's not in the clock tower anymore until she's looking for Peter and realizes that another set of vigilantes are on the scene.
She finally breaks down when she's led towards some paramedics by Robin, calling out for Peter, looking for him, the suit, anything, out in the crowd. She makes eye contact with Robin. She can't see his eyes from behind the domino mask. It's then she starts shaking.
"We ain't in Kansas anymore, Gwenny" she can hear Peter say and it makes it all worse.
Meanwhile Robin is assessing her and her green water stained clothes.