I'd need to know more, but if it's training the immune system not to overreact to the presence of an allergen, I suspect they're targeting specific protein strands that keep mast cells stable and from degranulating--which is what happens when you're exposed to a trigger.
So, yes, this could be significant in terms of calming down and reducing the over-priming of mast cells that triggers both normal and idiopathic reactions we see in mast cell diseases.
And even if it doesn't work (though I can't think of a reason why it wouldn't) this is still incredible. Holy shit, what a time to be alive.
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if the blurry man IS lou/tommy, i’d love for him to show up unannounced at bobby’s memorial thing. it’ll probably be the first scene of the premiere but i’d really like for it to happen AFTER the whale rescue. after it’s over hen and athena have to rush for their space adventure thing, while everyone else is just hanging around the firehouse.
(under a read more bc it got a bit long)
and then buck spots tommy in his civilian clothes hanging out by the bay doors and walks up to him like: “hey wha—what are you doing here?”
and tommy’s just playing it cool with: “wanted to check in, see how you all are doing.”
“we’re… we’re doing good. well, as good as we can be, but uh… we’re working on it.”
and tommy just looks at buck with his “you know eddie can have more than one friend, right” expression and says: “you know you don’t have to be okay, right?”
and then before buck can respond the alarm goes off and it’s all hands on deck. the geomagnetic storm hit and the 118 have to hastily get their gear on while maddie, sue, and josh have to rush back to dispatch.
and while buck is suiting up (just picture oliver trying to squeeze into kenny’s turnouts from the hot one’s episode), he notices that tommy isn’t… leaving? he’s talking to karen.
so when everyone else rushes to the truck, buck quickly stops by tommy and is like: “hey, don’t you have to go in?”
and tommy points at karen and the kids: “um. i was gonna stay with karen and watch the kids.”
“harbor doesn’t need you? surely they need every pilot they can get.”
(“buck!” chim shouts as he climbs into the front of the engine)
and tommy just kinda presses his lips: “i… got suspended. grounded for six months. turns out the LAFD is less lenient when you steal municipal property a second time, much less when you take said municipal property on a wild goose chase with the army.”
“… but you love flying.”
“evan—“
“no, no. don’t— this is my fault. i could have asked lucy or— or we could have found another way to get chim the cure—“
“evan. you needed my help. i was never going to say no.”
and buck’s just stunned for a moment before he blurts out: “can we talk? after…” he just gestures towards the truck. “after all this?”
and tommy just smiles and says: “sure.”
(“buck, we gotta go!” chim yells from off-screen.)
“but later, you’ve—“ and tommy grabs buck’s helmet from his hands and slaps it onto his head, with it covering his eyes. “—got a city to save, firefighter buckley.”
and buck just tilts the helmet back and gives his little coy tommy smile before running to the truck: “it’s a date!”
and boom we go into the emergencies, bucktommy reconciliation set up and ready for a later episode.
My dad raises grass-fed beef cattle and I help him sell it, mainly by maintaining an online presence. For a while, I kept having the most ridiculous conversations with people who I assume were marketing students. I didn't want to be rude so I'd try to let them down gently but this one guy just kept insisting that with his magical marketing skills he could grow our business.
What he could not seem to comprehend is that we could not grow our business, at least not without significant time and monetary investment. Cows take two years from pregnancy to the size that you can sell. If we buy adult cows, our margins become razor thin or even negative. Even if we somehow could acquire some cows, our barn and hay fields are already near maximum capacity. Renting another field would be relatively easy, building a bigger barn not so much.
Cows are living animals, they aren't widgets that can be produced infinitely. Besides that, many businesses inherently cannot grow, because if they do they'll become something else. The delicious bakery down the street cannot produce much more than they do, if they began mass marketing and production they'd eventually be selling the equivalent of Twinkies. We grow grass-fed, organic beef, if we expanded how long would that last? Eventually we'd become the very factor farms that we hate. Some things can only ever be made on a small scale and they are usually the best things.
But also, what are they teaching them at marketing school and how is it so disconnected from reality?
People kept trying to do this to my petcare business. “Let us build you a website! Let us buy you some ads! Let us print you flyers and cards!” I have exactly as much business as I can handle, and I’m happy with that. “But if you expand you could hire other people to do the work and pay them less, and raise your prices and eventually you can work from home!! Let us help you!” I’m doing this because I like playing fetch for a living, I like being outside moving around all day every day, I like spending time with each animal separately, I like being trusted by my clients with the keys and codes of their homes, it makes me feel proud. None of what you’re offering me is what I want. I don’t want a dozen miserable contractors who I pay 40% of each visit, I don’t want to try and wrangle and hire and vet people to do the part of my job that I like for me. That sounds bad. That’s a bad idea. And they looked at me like I was speaking an alien language. “But… website!! SEO! Ad buys! Targeted coverage! Constant growth!!” I don’t want any of that in my life it sounds fucking awful
One of the cruelties of capitalism is that if you want to do work you’re good at and love, a lot of the time your only option is to enter into some kind of business, and as soon as you do that, all the structural incentives of the system start trying to pull you away from the parts that you’re there for (i.e. the things that make life worth living) and towards various kinds of exploitation. Anyway, this also applies to writing and selling novels.
I agree with OP down to my bonessss. The best things are done with pasison by artisans, who deseve to be compensated respectfully, but aren't into their work from a place of greed or whatever misguided capitalist-brained bros think 'efficiency' is.
I'm plenty efficient, at getting things done the way i intend to.
i described to my econ-brain-rotten brother how i run my tattooing business and got the same responses as above.
It's like he absolutely didn't hear me when i explained the nuanced reasons i even started doing this work; I started tattooing because i was tired of the isolation of my (at that point) decade-long career in the animation industry. I was sick of my best work rotting on hard drives in shut down studios, of never getting to see anyone interacting with my art.
Moved to a big queer city, where my community got me started: queer tattooers patiently shared information and resources with me. early on, friends volunteered to let me experiment on their skin. Then they started offering to pay for materials, then more. Then they brought their friends to me...
I have a beautiful community of people who know me from the drag scene, from the poetry and writing scene, from the techno scene - and all these ppl come to me because they know me, met me, trust me, because they felt comfortable in my presence.
I only have like 1200 followers on my tattooing Instagram - which rly isn't a lot for a tattooer. But i stay busier than some ppl who have more followers - and im pretty sure that it's because 90% of the ppl following me have actually met me irl. I don't give out my info to just anyone. I have to have a nice interaction with them - and they with me - and i basically invite them to get to know my work, if i think they'd be interested, if they seemed excited about it.
I built my business out of love and care, and connection. I built it because i wanted more of these things in my life. I am making what i wanna see in the world.
Im deeply proud of what I've accomplished as a tattooer, exactly because i stuck to my own beliefs and built a business that is fully customized to me, what im excited about, my abiliy and disability levels, and my philosophical values. This part of my life is all mine, crafted and chiselled just how i want it.
I don't like getting up in the morning, so my sessions never start earlier than 1300. I have a hard time focusing alone + i wanna empower ppl who aren't artists to play with art + help ppl practice and engage their decision making and request making skills - so i design the tattoos with them sitting right next to me, being part of the art process. I don't like doing math and counting so i give my clients a sliding scale based on project complexity, and they get to choose how much they pay me. This also doubles as a way to give ppl more agency in the process of getting a tattoo. Etc etc it goes on and on - every aspect of the process is considered and phislophically and emotionally calibrated. I love what I've created and i love giving the gift of a well-crafted thing......
And after hearing me explain all that, my brother said my marketing wasn't efficient and my business isn't scalable...
I dunno, i think smtng abt capitalism legit gives ppl brain damage or smtng wtf
I think the ideal mutual is someone with some solid common ground but who also has a bonkers niche interest that’s totally foreign to you. It’s like a friendly educational experience
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Tumblr being the "piss on the poor" reading comprehension site makes sense when you realize that 79% of adults in the US are functionally illiterate. Same goes for Twitter and TikTok.
that's a real high number, sport. where'd you get it?
A blurb towards the top of the page states 54% but if you scroll down to "Literacy Statistics 2024-2025 (Where we are now)" it states 79% of american adults are illiterate as of 2024. (National Literacy Institute)
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