ice flight icy

We’re trying to decide which of these is a better option:

or

🦉🛸🦌

Guild: -chilly silence-

President: so the challenge to you all is a quilt with your interpretation and/or feelings towards our current “democracy”

Guild: 👏👏👏

How I spent my July 4th.

At the start I thought stitching “fuck you I won’t do what you tell me” for the last quarter would be therapeutic

I was correct.

I have one more line of embroidery and I think it needs to be bolder and messier than I started it.

Hard to tell in this light, and without ironing it, that the embroidery does get gradually bolder as it goes. Two strands at the top versus 5 at the bottom (6 for the started to be redone final line).

Not bad for first time doing appliqué.

[Image Source]

Clinical, Histopathological and Genetic Features of a Cutaneous Adnexal Polycystic Syndrome in Lykoi Cats: A Prospective Study of 10 Cases

Objectives

The Lykoi is a recently recognised feline breed with a unique coat phenotype caused by six variants of the Hairless (HR) gene. A specific severe cutaneous comedonal syndrome has been reported in this breed. The aim of the study was to carry out a clinical, histopathological and genetic characterisation of this syndrome.

Methods

Prospective data collection included clinical evaluation, skin biopsies for histopathology, trichoscopic examination of hair shafts, blood sampling for haematology and biochemistry, cutaneous swabs for bacteriological culture, and buccal swabs for DNA extraction and genotyping.

Results

In total, 11 privately owned Lykoi cats were enrolled, including those with varying degrees of skin involvement and one healthy cat. Cats were aged 1.5–7 years at the time of diagnosis. Clinical presentation was characterised by papular lesions and comedones, ranging from severe generalised forms (n = 6/10) to moderate regional forms (n = 2/10) and to mild scattered forms (n = 2/10). Histopathological lesions from skin biopsies revealed infundibular follicular cysts (n = 9/10), sebaceous gland (duct) cysts (n = 10/10) and sweat gland cysts (n = 5/10). Genetic analysis identified 5/6 described HR variants among the 10 affected Lykoi and the control Lykoi.

Conclusions and Relevance

This cutaneous syndrome shows a variable clinical severity that is not fully explained by genotype alone. The consistent presence of cysts from all three adnexal structures, even in clinically unaffected skin, supports the recognition of a novel skin condition, which we propose to name cutaneous adnexal polycystic syndrome (CAPS) in Lykoi cats. Further research is needed to elucidate its pathogenesis.

>>[Read Full Study]<<

I strongly encourage you to read the full study, it’s extremely interesting - although be warned, it does have visuals.

I’ve talked about the Lykoi breed before and I’m glad they’re finally getting more attention, I hope further research is done into CAPS.

Something I thought was interesting was how the asymptomatic Lykoi had an isolated sebaceous duct cyst, she is 3y at the time the sample was collected and the most common age of symptom onset appears to be 3.5y - 4y.

Pink noctuid moth (no common name), Philareta treitschkei, Noctuidae

It is found in Turkey, the Caucasus, the Balkans, Iran and the Levant.

✨⭐ Somewhere Out There ⭐✨