Alui

Ayo I know most of you followed me for something in mcyt but please appreciate how much time I put into drawing my dragon oc Caspian he takes a long time to draw,,,

After a moment he changed the music on his phone to what sounded like a Hatsune Miku song. Curiosity got the better of me, so I finally spoke up and said “is this Hatsune Miku?”

And he said “Yep. You looked uncomfortable, and I know Transgender women like Hatsune Miku, so I thought it might help.”

Full Transcript at the link; 3-minute listen.

Quote:

By taking biopsies from long COVID patients before and after exercising, scientists in the Netherlands constructed a startling picture of widespread abnormalities in muscle tissue that may explain this severe reaction to physical activity.

Among the most striking findings were clear signs that the cellular power plants, the mitochondria, are compromised and the tissue starved for energy.

"We saw this immediately and it's very profound," says Braeden Charlton, one of the study's authors at Vrije University in Amsterdam.

The tissue samples from long COVID patients also revealed severe muscle damage, a disturbed immune response, and a buildup of microclots.

This article mentions that ME/CFS is a "similar complex condition" but that's DEEPLY underreporting the similarities. The phrase "post exertional malaise" (now researchers are trying to replace it but this article uses that phrase) was INVENTED for ME/CFS. It's the only known condition, before "long covid", that causes these kinds of symptoms after exertion!

It's good to know for sure that it's the same mechanisms at play when the inciting viral infection is Covid and not, for instance, Epstein-Barr or RSV, but half the time it doesn't seem like researchers are making comparisons at all, just reinventing the wheel and acting like "long covid" is a totally new phenomenon with no previous point of comparison. There are literally drugs in human trials to try to treat the mitochondrial dysfunction in ME, this dysfunction is well-established and fairly well understood and I feel insane when ppl report on long covid without mentioning that there is already a named and studied condition that accounts for this subset of symptoms!!

SOME researchers are drawing comparisons but they're largely ME researchers who everyone else is largely cignoring because of the widespread perception that ME is a fake disease for lazy women.

That same perception btw is why "graded exercise therapy" (GET), or exercise gradually increasing in intensity, cwas for years the go-to treatment despite MOUNTAINS of evidence that it makes ME patients sicker. Some end up permanently bedbound and unable to even eat or drink without a feeding tube/IV because the damage is so bad! The GET recommendation was finally changed only in the past few years in the US and the UK, and many doctors hate that they're not allowed to recommend it anymore, because they insist despite the evidence that ME/CFS is psychological and ME patients are just "deconditioned" and too lazy to do anything about it.

Now the same kind of "treatment" is being recommended for long covid patients despite evidence showing exercise is having the same kinds of cellular effects as it does in ME patients. "Taking PEM into account" sounds gentler but I'm deeply concerned about the reinvention of GET for patients who meet all the criteria for an illness that's been shown definitively to become permanently worse with GET. This mitochondrial damage is progressive in ME, and there's no reason to believe patients who meet all the criteria of ME after Covid won't experience the same progression if they force themselves past their energy envelope in such a systematic way.

The additional finding that T cells — part of the immune system's arsenal — had infiltrated the muscles of long COVID patients also caught Iwasaki's attention, possibly indicating "an autoimmune response within the muscle cells."

and no, this isn’t me saying “write that messed up, disgusting thing” because while, yes, write it if it’s what you want (I myself enjoy writing dark fics, something I believe would be considered “vile” to a lot of people), this is me saying in a world of censorship and capitalism, ao3 really is a treasure.

Slays.bySarah on IG

Etoilesroses on IG

Phleshe on IG and maybe on here? 

Feycrafts on twitter

KSHAW_tv on Twitter

Kagoneko on twitter

Hotboybebop on Twitter 

Queer_Elf_Club on Twitter 

I was bulled extensively in elementary school, but 1. Mostly by my teachers and 2. Not during this, because we ALL had PBS Nature and as Deer, I was allowed to gouge, kick, bite, keep running even after being grabbed, or body-check the larger children into the picnic tables and other architecture.

You know, for realism.

Random doodle dump from patrron

Bonus sketch :

Fortunately, banks no longer just ask 'did you make that transaction' they want to make sure you weren't scammed into making that transaction and 5mins after their call will give away all your money anyway.

This is an honest to goodness life saving movement and I cannot be happier banks are adopting it

Unfortunately, it meant I had to have the most embarrassing financial call of my life

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Me: Ah yeah I was just trying to tip a tumblr blog

Cash: right and were you directed there by a Facebook link? An Instagram advert?

Me: no I was just on tumblr...on purpose

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Caah: and this person asked you for money?

Me: oh no they just had a funny story, which happened to be about money and I thought, "wouldn't it be funny if I tipped them"

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Me: * covering a reblog by reblog update on the adventures my mutual was having *

Cash: okay I don't think that can actually happen though..

Me: It might not have, but i was happy to tip them just because it was funny

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Cash: and how well do you think you know this person?

Me: *considers explaining how much I know about a beloved mutual without ever knowing their name or face* ... I have no idea who this person is