Dyke March London 2026
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ojovivo
macklin celebrini has autism
wallacepolsom

#extradirty
One Nice Bug Per Day

tannertan36
Keni

❣ Chile in a Photography ❣
🪼

@theartofmadeline
we're not kids anymore.
2025 on Tumblr: Trends That Defined the Year
he wasn't even looking at me and he found me
Lint Roller? I Barely Know Her
TVSTRANGERTHINGS
"I'm Dorothy Gale from Kansas"
Noah Kahan
Cosimo Galluzzi
occasionally subtle

seen from Malaysia
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@transratsactivist
Dyke March London 2026
** TERFs, SWERFs, transmisogynists, & the like who interact with this post will be shamed & blocked 💖 **

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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x
anyway everyone go donate to Lambda e.V.
Look at my birthday cake...
I've been meaning to make a post talking about my stroke because y'all got bits and pieces of the recovery but I never actually told the story of HOW it went down and the thing is the type of stroke I had is usually the type young people have and since having mine i've now heard multiple stories of people under 40 having very similar strokes and the scary thing is, is that they didn't get help right away. Because you're young and healthy and sure you feel weird but it'll pass right? but it doesn't, and it gets worse, and by the time you get to the hospital (some people literally take days to go) the deficits are worse and recovery is harder.
so here's a super long post about strokes in general, and mine in particular/what I went through.
women in stem

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Cute Blue Rays Bowl 🥣 available
it fucken WIMDY
girk at my work discovered my terrible secret
“girk at my work”
“girk at my work”
Nishimoto Ryota
a piece of wood carved to fit perfectly into a zippered plastic bag

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watercolors by trans artist tuesday smilie
i think we should be talking about the semi-recent advancements in cystic fibrosis treatment like all the time every day. there hasn’t been a drug like this since AZT medications for HIV infection it is truly fucking miraculous and very important
basically: cystic fibrosis is a genetic disease which makes the mucous a person generates extra sticky. it used to kill people in infancy, then with advancements in medical tech it killed people in young childhood, and until very recently cystic fibrosis patients could expect to live until about thirty years old with consistent painful lung infections and complications.
in 2019 the FDA approved a drug called trikafta (which is really three drugs in one) for cystic fibrosis treatment. what it essentially does is patch up the malfunctioning proteins that cause the extra sticky mucus. trikafta is effective on about 90% of cystic fibrosis patients.
people who had spent their entire lives in and out of hospitals, on and off of ventilators, suffering from pneumonia and sometimes treated through painful procedures like intubation took this drug, got out of bed, coughed up an entire lifetimes worth of mucus out of their lungs over the course of a few hours, breathed clearly for perhaps the first time in their lives, and now go on to live well into their seventies.
like isn’t that insane. isn’t that amazing. doesn’t that give you hope for the future of medical advancements and treatment. fuck. i think about it all the time……
There’s a WHAT.
For WHAT.
It's been amazing!
My ward is the respiratory ward - CF is one of the things we specialize in.
Since this med came out we haven't had a SINGLE CF admission to the ward
There used to always be a CF patient spending a couple of months with us at a time
There's a man who is 23 years old who I was sure would not survive his next admission (aim saturations 85% is end stage lung disease)
There's a set of the local frequent flyers that we all know so well
Except
No we don't
On the CF specialist ward (with reasonable staff turnover)
Half the staff have probably never even seen a CF patient
They are going to live
For the people asking "well how do we know people are living that long if it's so new????" Here's a page from the CF foundation about life expectancy.
Additionally, it should be noted that metrics like life expectancy are in no way a guarantee of... Anything. There are significant outlier CF patients who are at an advanced age now despite the odds due to a variety of different factors, having lived the majority of their lives before the development of modulators.
But the fact remains that the odds are better now than they have ever ever been before, by leaps and bounds. It isn't cured, and many patients still need significant treatment in addition to Trikafta, but it is so much better than anyone could have dreamed of twenty years ago, and that is a triumph.
Yes! My sister has a serious form of cf and finally is living a more comfortable and active life. She was also part of many of the clinical trials leading to these breakthroughs due to the nature of her cf. It's been very exciting to see.
SO YEAH HI LMAO I'm a CF patient who's presently taking Trikafta, and I have been since 2022. Before that, I was taking Kalydeco (ivacaftor), which is a component in Trikafta.
These medicines are incredible. My lung function's now basically at healthy-person-without-CF levels, and so's my sweat chloride. I still take pancreatic enzyme supplements, and I still do my respiratory treatments for maintenance reasons, but my overall health is still SO MUCH BETTER NOW. My weight is stable, I don't get anywhere near as many sinus infections, my migraines don't last as long.
Another incredibly cool thing is that they're seeing recovery from lung damage in kids who are on Trikafta and other CFTR modulators - and slight recovery in adults too. My own chest X-rays show that my bronchiectasis has gotten just a little better.
I was born in 1981, and it's wild to see how much the treatments and prognoses for CF patients have improved. Adult CF clinics are a thing now. More and more of us are living longer.
I'll always wish that more of my friends had made it this far, and gotten access to these medications. But I'm so grateful that I have this access, and I'll keep on keeping on in their memory.
“What if poor people abuse the system?”
The system intrinsically abuses poor people.
Hope this helps.
"What if poor people abuse the system?"
Rich people abuse the system far more and out of pure greed, not necessity or desperation so idrc about that
Really Big Coin Skrekkøgle
This is our Really Big Coin. It is big because it makes other things look small when photographed next to it. Actually, it is a 20:1 replica of the EUR 50-cent, you see it being milled out here. We needed to do quite a bit of sanding, lacquering and smudging to obtain the desired look and some climbing to get into required shooting position (you need to get up real high to take good pictures). The result is a short series of photographs, attempting to visually scale down real-sized objects.
Images and text via
what the fuck
teamwork makes the dream work. and dreamwork. makes shrek
fantastic. i love it. i posted this after my wife said it yesterday and as i was doing it i was like "this can't be an original thought. as soon as i hit post someone's going to say 'you stole this from a tweet from 2014' and i'll say 'no, i stole it from my beautiful wife.'"

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After 13 years of this, it's still funny to me that detailing a full mental breakdown on tumblr is standard fare, but posting a nice selfie is a fraught decision.
this is the correct way around and every other social media site is wrong
– Directors' Commentary, Project Hail Mary (edited slightly)