The body is complex, and hormones do many things. Hell, when puberty starts there are many effects and mood swings. All I am saying is that if someone is looking to take a medication with a massive number of things it changes,it is good to know what all of the probable side effects are, and all of the unlikely ones. The issue is that it seems like people have been over-inflating the probability of it changing your sexuality, which is scaring people. What we should be doing, instead of saying its impossible, is reassuring them that it is very very unlikely, even though still possible, because if they hear that its impossible, take hrt, and it happens, then they will likely feel even worse and horrible about it. What we need to do is, instead of spreading medical misinformation to try and soothe people, figure out their specific concerns and address those.