Really Autistic About Breaking Bad

addition: [tags staff] what the fuck is your problem? can you leave her alone? [a shit ton of posturing that has nothing to do with OP]

you have a body

that’s it

you’re beautiful

you win

it would be so awesome

when it's framed as a "so just get married for legality reasons" and im like. you mean like how gay people married/marry people of the opposite gender for legality reasons? and that's considered to be a symptom of a problem, not the solution? you want people to "just" get married against their will because it's the only solution this system has available?

if people cannot or will not get married for whatever reason -- not just for being aromantic, but, say, due to inefficient disability support measures within marriage, because of having had bad experiences with marriage in the past, because of being polyamorous, because some element of marriage is ineffective, unwanted, limited, discriminatory, or hell, because you can't find somebody to marry or nobody wants to marry you, or maybe because you just plain don't want to without there being a distinct Reason -- then it's a problem that this is the only framework in place for people to be afforded certain legal and social protections.

i am glad for others that more people can get married, but it's a flawed institution with gaping holes that isn't for everyone and builds social structures that leave so many people behind and unsupported. this is abundantly obvious in the way that we saw why people pushed for the need for equal marriage in the first place.

that's what's said when making a point that it's a social construct. and also what's meant (partially) when pushing against the idea that "love" as concept isn't at the core of queer (amongst others hinted at in this post) activism, because it's about building better structures. if the only people we care about are those we "love" within a family unit, or those who successfully manage to pretend that unit without actually really wanting it, and if not being in that unit for whatever reason means that care isn't going to be/is no longer afforded, then are we really doing any better than heteronormativity?

Full Transcript at the link; 3-minute listen.

Quote:

By taking biopsies from long COVID patients before and after exercising, scientists in the Netherlands constructed a startling picture of widespread abnormalities in muscle tissue that may explain this severe reaction to physical activity.

Among the most striking findings were clear signs that the cellular power plants, the mitochondria, are compromised and the tissue starved for energy.

"We saw this immediately and it's very profound," says Braeden Charlton, one of the study's authors at Vrije University in Amsterdam.

The tissue samples from long COVID patients also revealed severe muscle damage, a disturbed immune response, and a buildup of microclots.

This article mentions that ME/CFS is a "similar complex condition" but that's DEEPLY underreporting the similarities. The phrase "post exertional malaise" (now researchers are trying to replace it but this article uses that phrase) was INVENTED for ME/CFS. It's the only known condition, before "long covid", that causes these kinds of symptoms after exertion!

It's good to know for sure that it's the same mechanisms at play when the inciting viral infection is Covid and not, for instance, Epstein-Barr or RSV, but half the time it doesn't seem like researchers are making comparisons at all, just reinventing the wheel and acting like "long covid" is a totally new phenomenon with no previous point of comparison. There are literally drugs in human trials to try to treat the mitochondrial dysfunction in ME, this dysfunction is well-established and fairly well understood and I feel insane when ppl report on long covid without mentioning that there is already a named and studied condition that accounts for this subset of symptoms!!

SOME researchers are drawing comparisons but they're largely ME researchers who everyone else is largely cignoring because of the widespread perception that ME is a fake disease for lazy women.

That same perception btw is why "graded exercise therapy" (GET), or exercise gradually increasing in intensity, cwas for years the go-to treatment despite MOUNTAINS of evidence that it makes ME patients sicker. Some end up permanently bedbound and unable to even eat or drink without a feeding tube/IV because the damage is so bad! The GET recommendation was finally changed only in the past few years in the US and the UK, and many doctors hate that they're not allowed to recommend it anymore, because they insist despite the evidence that ME/CFS is psychological and ME patients are just "deconditioned" and too lazy to do anything about it.

Now the same kind of "treatment" is being recommended for long covid patients despite evidence showing exercise is having the same kinds of cellular effects as it does in ME patients. "Taking PEM into account" sounds gentler but I'm deeply concerned about the reinvention of GET for patients who meet all the criteria for an illness that's been shown definitively to become permanently worse with GET. This mitochondrial damage is progressive in ME, and there's no reason to believe patients who meet all the criteria of ME after Covid won't experience the same progression if they force themselves past their energy envelope in such a systematic way.

The additional finding that T cells — part of the immune system's arsenal — had infiltrated the muscles of long COVID patients also caught Iwasaki's attention, possibly indicating "an autoimmune response within the muscle cells."