The hospital treats hundreds of these cases every year. All share a common culprit: Lanmaoa asiatica, a type of mushroom that forms symbiotic relationships with pine trees in nearby forests and is a locally popular food, known for its savory, umami-packed flavor. In Yunnan, L. asiatica is sold in markets, it appears on restaurant menus and is served at home during peak mushroom season between June and August.
One must be careful to cook it thoroughly, though, otherwise the hallucinations will set in.
"At a mushroom hot pot restaurant there, the server set a timer for 15 minutes and warned us, 'Don't eat it until the timer goes off or you might see little people,'" says Colin Domnauer, a doctoral candidate in biology at the University of Utah and the Natural History Museum of Utah, who is studying L. asiatica. "It seems like very common knowledge in the culture there."   Â
[...]
He and his team are still trying to identify the chemical compound responsible for the hallucinations in L. asiatica. Current tests suggest it is not likely related to any other known psychedelic compound. For one, the trips it produces are unusually long, commonly lasting one to three days after an onset of 12 to 24 hours, and in some cases even causing hospital stays of up to a week. Because of the extraordinarily long duration of these trips and the chance for prolonged side effects such as delirium and dizziness, Domnauer has yet to try the raw mushrooms himself.
These mega-trips might help to explain why people in China, the Philippines and Papua New Guinea do not seem to have a tradition of purposefully seeking out L. asiatica for its psychoactive effects, according to Domnauer's findings. "It was always just eaten for food," Domnauer says, with hallucinations being an unexpected side-effect.
There's another curious factor: other known psychedelic compounds also usually produce idiosyncratic trips that vary not only from person to person but also from one experience to the next within the same individual. With L. asiatica, though, "the perception of little people is very reliably and repeatedly reported", Domnauer says. "I don't know of anything else that produces such consistent hallucinations."
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