#diffusion tensor imaging

Studies looking at dysphoria focii (e.g. social dysphoria, bottom dysphoria, top dysphoria) as compared with brain stucture

Applications in Comprehensive Health Assessments in Diffusion Tensor Imaging:

In recent times, Diffusion Tensor Imaging (DTI) has expanded its scope from neuroscience to encompass full-body health evaluations. While traditionally utilized in neurological imaging, DTI's capability to analyze tissue microstructure has spurred interest in its potential for identifying and tracking systemic health issues.

One promising area for DTI application lies in assessing musculoskeletal health. By examining water molecule diffusion within muscle fibers and tendons, DTI offers insights into tissue integrity, inflammation, and injuries. In athletes and those involved in rigorous physical activities, DTI may aid in early detection of muscle strain, tendonitis, or ligament damage, facilitating timely intervention and rehabilitation.

Additionally, DTI shows promise in evaluating cardiovascular health by analyzing microstructural properties of cardiac muscle tissue. Changes in diffusion metrics like fractional anisotropy (FA) and mean diffusivity (MD) may indicate underlying myocardial conditions such as fibrosis, hypertrophy, or ischemia. Combined with traditional cardiac imaging techniques, DTI could enhance diagnostic accuracy and help stratify cardiovascular disease risks.

In abdominal imaging, DTI offers insights into microstructural changes linked with liver fibrosis, cirrhosis, or hepatic cancers. By quantifying diffusion alterations within hepatic tissue, DTI complements existing techniques like magnetic resonance elastography (MRE) and diffusion-weighted imaging (DWI), offering a holistic view of liver health.

Moreover, DTI holds promise in evaluating renal function by assessing diffusion properties within renal tissue and collecting ducts. Changes in diffusion metrics may signal renal fibrosis, inflammation, or impaired water transport, aiding in early detection and management of renal diseases.

Integrating DTI into multi-modal imaging protocols for comprehensive health assessments could provide deeper insights into systemic health and organ function. Despite its potential, challenges such as sensitivity to motion artifacts, scan duration, and data processing requirements need addressing for wider clinical adoption. Additionally, standardization and validation of DTI findings outside the brain are essential for reliability across different platforms and patient groups.

Despite hurdles, incorporating DTI into full-body health evaluations offers a promising avenue for advancing understanding of systemic health and disease. With ongoing technological advancements and research, DTI could emerge as a crucial tool for early detection, proactive management, and improved outcomes across various medical conditions.

Publisher: In-Sight Publishing Publisher Founding: March 1, 2014 Web Domain: http://www.in-sightpublishing.com Location: Fort Langley, Township of Langley, British Columbia, Canada Journal: In-Sight: Independent Interview-Based Journal Journal Founding: August 2, 2012 Frequency: Three (3) Times Per Year Review Status: Non-Peer-Reviewed Access: Electronic/Digital & Open Access Fees: None…

Characterizing tumor invasiveness of glioblastoma using multiparametric magnetic resonance imaging

J Neurosurg 132:1465–1472, 2020

The objective of this study was to characterize the abnormalities revealed by diffusion tensor imaging (DTI) using MR spectroscopy (MRS) and perfusion imaging, and to evaluate the prognostic value of a proposed quantitative measure of tumor invasiveness by combining contrast-enhancing (CE) and DTI abnormalities in patients with glioblastoma.

METHODS Eighty-four…

Utility of a Quantitative Approach Using Diffusion Tensor Imaging for Prognostication Regarding Motor and Functional Outcomes in PatientsWith Surgically Resected Deep Intracranial Cavernous Malformations

Neurosurgery 86:665–675, 2020

Resection of deep intracranial cavernous malformations (CMs) is associated with a higher risk of neurological deterioration and uncertainty regarding clinical outcomes.

OBJECTIVE: To examine diffusion tractography imaging (DTI) data evaluating the corticospinal tract (CST) in relation to motor and functional outcomes in patients with surgically resected deep CMs.

ME…

Correlation of magnetic resonance diffusion tensor imaging parameters with American Spinal Injury Association score for prognostication and long-term outcomes

Neurosurg Focus 46 (3):E2, 2019

Conventional MRI is routinely used to demonstrate the anatomical site of spinal cord injury (SCI). However, quantitative and qualitative imaging parameters have limited use in predicting neurological outcomes. Currently, there are no reliable neuroimaging biomarkers to predict short- and long-term outcome after SCI.

METHODS A prospective cohort of 23 patients with…

Correlation of magnetic resonance diffusion tensor imaging parameters with American Spinal Injury Association score for prognostication and long-term outcomes

Neurosurg Focus 46 (3):E2, 2019

Conventional MRI is routinely used to demonstrate the anatomical site of spinal cord injury (SCI). However, quantitative and qualitative imaging parameters have limited use in predicting neurological outcomes. Currently, there are no reliable neuroimaging biomarkers to predict short- and long-term outcome after SCI.

METHODS A prospective cohort of 23 patients with…