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Blue Brain Project | Mouse Neocortex Tractography
"View from below the neocortex rendered at 3% density. Showing long distance connections (white matter) between regions of the neocortex. Neurons are colored by morphological types and algorithmically synthesized." [EPFL | Switzerland | 2005—2020]
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In neuroscience, tractography is a 3D modeling technique used to visually represent nerve tracts using data collected by diffusion MRI. It uses special techniques of magnetic resonance imaging (MRI) and computer-based diffusion MRI. The results are presented in two- and three-dimensional images called tractograms. (Wikipedia)
Intraoperative MRI–based elastic fusion for anatomically accurate tractography of the corticospinal tract
Intraoperative MRI–based elastic fusion for anatomically accurate tractography of the corticospinal tract
Neurosurg Focus 50 (1):E9, 2021 Tractography is a useful technique that is standardly applied to visualize subcortical pathways. However, brain shift hampers tractography use during the course of surgery. While intraoperative MRI (ioMRI) has been shown to be beneficial for use in oncology, intraoperative tractography can rarely be performed due to scanner, protocol, or head clamp limitations.…
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Tractography-Guided Deep Brain Stimulation of the Anteromedial Globus Pallidus Internus for Refractory Obsessive-Compulsive Disorder
Neurosurgery 86:E558–E563, 2020
Obsessive-compulsive disorder (OCD) is a disabling psychiatric disorder, mainly treated with psychotherapy and pharmacotherapy. Surgical intervention may be appropriate for patients with treatment-refractory OCD. Deep brain stimulation (DBS) is an alternative for previously common ablative surgical procedures. Tractography has been proposed as a method for…
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Probabilistic Tractography to Predict the Position of Cranial Nerves Displaced by Skull Base Tumors: Value for Surgical Strategy Through a Case Series of 62 Patients
Probabilistic Tractography to Predict the Position of Cranial Nerves Displaced by Skull Base Tumors: Value for Surgical Strategy Through a Case Series of 62Â Patients
Neurosurgery, Volume 85, Issue 1, July 2019, Pages E125–E136
Predicting the displacement of cranial nerves by tumors could make surgery safer and the outcome better. Recent advances in imaging and processing have overcome some of the limits associated with cranial nerve tractography, such as spatial resolution and fiber crossing. Among others, probabilistic algorithms yield to a more accurate…
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Probabilistic Tractography to Predict the Position of Cranial Nerves Displaced by Skull Base Tumors: Value for Surgical Strategy Through a Case Series of 62 Patients
Probabilistic Tractography to Predict the Position of Cranial Nerves Displaced by Skull Base Tumors: Value for Surgical Strategy Through a Case Series of 62Â Patients
Neurosurgery, Volume 85, Issue 1, July 2019, Pages E125–E136
Predicting the displacement of cranial nerves by tumors could make surgery safer and the outcome better. Recent advances in imaging and processing have overcome some of the limits associated with cranial nerve tractography, such as spatial resolution and fiber crossing. Among others, probabilistic algorithms yield to a more accurate…
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Prospective Tractography-Based Targeting for Improved Safety of Focused Ultrasound Thalamotomy
Prospective Tractography-Based Targeting for Improved Safety of Focused Ultrasound Thalamotomy
Neurosurgery 84:160–168, 2019
Focused ultrasound thalamotomy (FUS-T) was recently approved for the treatment of refractory essential tremor (ET). Despite its noninvasive approach, FUS-T reinitiated concerns about the adverse effects and long-term efficacy after lesioning.
OBJECTIVE: To prospectively assess the outcomes of FUS-T in 10 ET patients using tractography-based targeting of the ventral…
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Prospective Tractography-Based Targeting for Improved Safety of Focused Ultrasound Thalamotomy
Prospective Tractography-Based Targeting for Improved Safety of Focused Ultrasound Thalamotomy
Neurosurgery 84:160–168, 2019
Focused ultrasound thalamotomy (FUS-T) was recently approved for the treatment of refractory essential tremor (ET). Despite its noninvasive approach, FUS-T reinitiated concerns about the adverse effects and long-term efficacy after lesioning.
OBJECTIVE: To prospectively assess the outcomes of FUS-T in 10 ET patients using tractography-based targeting of the ventral…
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