In all seriousness, my perspective on this is that you can't necessarily be an absolutist about things like it. It also strikes me as a very culturally Christian thing, 'thou shalt not kill' being extended to animals in the assumption that death is an absolute evil and a sin, etc etc, but that's not something I've given enough thought to to articulate properly.
Let's assume a decent farming situation, as is the intent of a lot of activism to ensure is universal - if that animal lived a content life and was slaughtered in the most painless way we can manage, I'm fine with eating it. In that situation, and hell even in many not-ideal farming situations, that animal had an exponentially better life than it would have had in the wild. It was fed and watered well, protected from predators and disease, and its death was hopefully peaceful, quick, and painless - in the wild, that animal would have lived in a state of constant stress trying to make sure it gets its next meal without becoming something else's next meal, not to mention the prevalence of disease and parasites, and it would likely have died violently or from sickness. Nature is not some uwu pretty Arcadian archetype like some people seem to think.
As far as I'm concerned, it's not unethical to eat that animal and use its hide, or indeed other parts of it. It's been extracted from the violence of nature to the point of having a downright idyllic lifestyle by humans, and I am perfectly okay with the humans in return getting food and clothing. I'm as much for reducing cruelty with lab-grown meat or plant-based fake meat as the next ethical human, but it's not unethical to eat meat. That's an absolutist stance that is fundamentally incompatible with, in my opinion, reality. Frankly, there are plenty of humans who need it - I know someone who actually is required by their dietician to eat meat because a plant-based alternative wouldn't sustain them and they'd become severely anaemic without it. I'm gluten free, a vegan diet would either leave severe deficiencies in my own diet or give me regular stomach issues. If I need meat, as many if not most humans do since we're omnivores, and I get that meat in the absolute least amount of cruelty-per-meat I can humanly manage, I'm cool with that.
This is of course why I am opposed to cruel farming practices, despite eating meat. That's not a contradiction.
And that's just the situations where slaughter is required. The takes I've seen on wool are asinine. Sheep need to be sheared. It is bad for them to just let them be. We have bred them over millennia to need shearing. The wool gets too heavy for them to survive falling in water, too warm and dense for them to survive hot weather or clean themselves, and it is a fucking breeding ground for parasites and shit when it gets dirty. You want the sheep to get flystrike? Stop shearing them and that's what happens. We don't dock lambs' tails for no reason, we do it because they get fuckin necrotic infection from flies if you don't. It would be cruel not to shear them. The only people who badly injure sheep when shearing them are incompetents nobody invites back, but a few nicks are inevitable because, funnily enough, sheep don't really understand the phrase "sit still please while I give you a glorified haircut."
But no, because PETA and shits like them are performative fucking absolutists who misrepresent shearing as skinning, wool is becoming so hard to sell that farmers are having to just dispose of it because it'd cost more to sell it than the money they'd make. And instead, people are making clothes out of FUCKING PLASTIC.
That's what your fucking vegan leather is. Plastic. Polyester is a kind of plastic. None of this shit will be good for the environment when it inevitably breaks down, and it breaks down exponentially faster than actual leather, wool, etc. Leather and wool are better materials and better for the environment especially when they're farmed ethically, but because it doesn't suit a pretentious fucking performative absolutism about using animal products, people think it's evil. Even that fucking supposedly good pineapple leather, Piñatex, is plastic. I was so fucking disappointed to learn that when I googled it. But because people hear "pineapple leather" they think it's a good vegan alternative to leather, when it just isn't, and you really don't need an alternative to leather. If you're slaughtering a cow who's lived a content and happy life ethically, there's no reason not to use the skin aside from it not being economically viable, which it is becoming because this performative bullshit sells the idea that leather is evil, despite the fact it's better for the environment and you need less of it because it doesn't break down into unbiodegradable bits into nature where it can fuck up anything it gets into and doesn't deteriorate as quickly. An actual leather jacket will last decades. Plastic leather, that won't be worth wearing in less than one decade.
I would much rather wear the wool of a few healthily-shorn sheep and the leather of maybe half a cow and have that last half a lifetime or longer than keep buying more and more shitty plastic clothes that release microplastics into the ocean and soil for just as long. But because of Vimes' Boots Theory, I kinda have to wear the shitty plastic for now, at least until I get to a point in making my own clothes where I've made them all out of better materials... read, wool, leather, and natural textiles like cotton and linen.
And then there's the shits who think it's inherently cruel because of consent or whatever. That's insane. If you try to anthropomorphise animals to the point of trying to apply consent to them you end up classifying nearly all of them as serial fucking rapists. You can't apply that argument to animals who fundamentally don't understand the concept. Have you met sheep. There is absolutely nothing behind those eyes. Categorically stupid animals. Especially when, as before, they've been bred to need our help. You can harangue over the ethicality of doing that millennia ago, but it's a pointless thought experiment when the best thing to do is just take care of the damn sheep and cows and whatever. Plus, if we stopped taking care of them, where the hell are they supposed to go? Go free and wreak havoc on the ecosystem? Wild deer and goats and shit are already damaging the environment, we don't need to add a bajillion cows and sheep and everything to that. Better to just keep taking care of 'em and harvesting what we get from them as ethically as possible.
All of this stemming I think from a (largely USAmerican, in my experience) complete detachment from and ignorance to the actual processes of farming and where food and textiles come from when combined with a puerile pseudo-Christian obsession with absolutist concepts of sin. It's not a sin to eat a steak. It's unethical to treat the cow that steak came from like shit. Long as that meat is coming from a cow that had a good life and as painless a death as possible, I'm fine eating it and wearing its leather.