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let's talk about Bridgerton tea, my ask is open

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@treenostalgia
Jousting at the festival to impress your lady love!!!

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in a galaxy far, far away
vampires are so full of shit. "oh the human race is beneath us, you're just livestock to us" I don't think you know what livestock is. do you feed us? care for us? protect us from predators? no. you just slink around dark alleys and ambush people. that's not what a higher being does. that's a bottom feeder. a parasite. karate punches your head off
She Would Say That. She would DO that.
creature found in bathroom at bathtime
some friendship dynamics i doodled that i love a lot because im a certified FRIENDSHIP LOVER from the board of FRIENDIRECTORS on planet PLATONIC

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I can understand how "modern person thrown into the past gets by pretending to be a healer/doctor" is as surprisingly common of a trope as it is. I mean I'm fluent enough at bullshitting to be pretty sure I could pull it off to impersonate a doctor in any time pre-1800s. If I have no idea what something is or how to treat it, I could just get the opinion of the other whatever-passes-as-medical-professionals around, but if their suggestions sound like bullshit I'm not doing it. And I'll beat the shit out of anyone suggesting bloodletting or mercury. With my healing stick. I've tied little bells on it, that jingle comically with every smack.
The awesome curative powers of my healing stick come from two separate sources: Placebo, and me using it to beat anyone trying to give my patients mercury.
Ooooh you reminded me of that protocol I wrote about how to reinvent penicilin with only alchemical tools. You know. Just in case I did end up dumped in the past and needed a stable income.
w
what's the protocol?
I am so glad you asked! I unfortunately lost the protocol because it was probably on my laptop, but I remember the broad strokes. So! In case anyone does end up stuck in the middle ages and can find a kindly old alchemist willing to lend you his gear, here's the revamped Penicilin (Re)Discovery Protocol!
0. WASH YOUR GODDAMN HANDS.
We're not working in a lab here, cross-conatamination WILL happen. Your job is to minimize it as much as possible. If you end up in a place where soap hasn't been invented yet, wash your hands in distilled alcohol. Your skin won't thank you, but you can afford all the nice hand creams after you cure the plague and get rich.
Find some Penicillium mushrooms!
Yes, penicilin is produced by mushrooms, though Ascomycotes are usually called moulds, it's a fungus, and it makes me laugh to call it a mushroom. Plus, in the middle ages, mushrooms were known to have medicinal properties, so you'll get a lot farther by calling them mushrooms rather than molds.
First thing you need: mouldy fruit. Oranges, or cantaloupes are preferred.
Here's the thing: mold is everywhere, so getting it will be the easiest part. The tricky part start with identifying the correct mold. You don't want to feed your patients black mold, do you?
So. Leave some fruit out. The more the better, because you want to up your chances. Then let it rot in warm and humid places. After a while, pick any fruit that looks white on the outside and green in the middle:
Not the best picture, but that's what it should look like.
2. Transplanting your (potential) Penicillium mushrooms
Until you get it on a plate it's damn near impossible to tell which mold you got. Get ready for some trial and error because you will have to sift through a lot of unwanted mold. You might want to wear a mask.
First you need something to transplant it onto. Making modern agar plates is probably impossible but thankfully not needed. You just need:
Glass plates (the kind that can be closed, you want to minimize cross contamination)
1-2 cup of Hot water (preferably distilled, ask your alchemist if he can do that)
1 cup whole milk (should be 13g of lactose per cup, if your Penicillium won't grow adjust the water-milk ration in favor of milk)
If available: Instead of milk use corn steep liquor. Unfortunately only available after America was discovered, so YMMW, but Penicillium LOVES this stuff. It will make your life SO much easier if it's available.
Pinch of salt
1 teaspoon Yeast extract (get it from a baker)
3-6 teaspoons Gelatin (get it from a butcher)
Disclaimer: The ratio of each of the ingredients will have to be adjusted depending on the purity of the ingredients and on the conventional measuring sizes of the place you end up.
Gently mix it all in and pour out into the plates, let it solidify. If you end up dumped far enough that such refinement isn't possible, make bone broth and strain it through cheesecloth several times to make it as clear as possible, then mix it 5/6 broth and 1/6 milk. Again, if available, use corn steep liquor, but if not milk is fine. Add gelatin (should still be able to get it from the butcher) as needed to solidify it. I'm afraid experimentation will be needed depending on the resources you will be working with.
When you're done, you should have something like this:
Now that you have your plates, run an inoculation loop through a flame to sterilize it.
Something like this. Wave it through the air to cool it so you don't kill your mold, grab it from your fruit and geeeeeently spread it on top of your improvised agar without breaking the surface of the gelatin!
You can see the motions on this one pretty well. Close your plates, stack them about a meter/3ft from the fireplace. Judge for yourself, but ideally somewhere you would consider comfortably warm (20-24Β°C).
3. Identifying your Penicillium Mushrooms
If all went well, you are going to have something that looks like this:
Well, realistically, it will look something like this:
We're not actually doing it in a lab, after all. But IDEALLY, it will look like the above. It doesn't have to be perfect, you just need to be able to identify Penicillium molds for now.
IDEALLY, on the plate that matches the description of the penicillium mold you'll see an exclusion zone of bacteria around the mold, like the fourth plate in the second row, so you know you have a potential winner, but if you managed to avoid bacterial growth you need to take a few extra steps.
Penicillium molds have characteristic rings of growth, grey-green-white rings. They're easy to differentiate from bacteria because the molds are fuzzy and the bacteria as smooth and slimy. In the above picture, there are four plates that potentially have what we want, and two are less certain than others. Wash out the unwanted ones, make new agar plates, sterilize your inoculation loop and transplant your best candidates. You might need to do this several times.
Two types are confirmed to produce penicilin: P. chrysogenum and P. rubens.
The former is far more widely used today, but since we're sourcing them from literally thin air, we're more likely to get P. rubens, but unless you're a mycologist you probably won't be able to tell the difference. Thankfully you won't need to, because they both produce penicillin. Which brings me to the next step.
4. Confirming it's the penicillin producing mushroom
We're gonna need more agar plates for this one, and believe it or not, you're gonna need to mix blood into your agar. Wash your hands THROUGHLY.
(Theoretically you can get away with just milk, but identifying the correct bacterial colony on white agar is going to be a nightmare, so just add some sheep blood to your agar, conventionally it's about 5% by volume but you might need more to make it)
You need some gram-positive bacteria, preferably of the Bacillota type. Please don't go out and find a patient with fucking botulism or tetanus, you need to live long enough to make the cure. Instead, if you have a vagina, scrape some of the white, mucousy stuff from there and plant it on your plate. If you don't have your own vagina, a borrowed one is fine. Penicilin also works on Treponema pallidum, so if you get a syphilis-affected prostitute that should also work. Just wear gloves.
Ideally you get something like this.
This is actually Lactobacillus brevis, but Lactobacillus colonies all look relatively the same. The important thing is that it's all gram-positive, and will therefore be affected by penicillin.
Take new plates again, plant your Penicillium mold in the middle, and the bacteria all around it, getting as close to the center as possible. You can put down a paper marker for the mold. Wait for about 20 days.
Ideally, on at least one plate, you will get something like this:
This is literally a textbook example of testing antibiotics, but the Zone of Inhibition is what you're looking for. It means the mold is releasing a compound to kill the competing bacteria for resources, in this case, Beta-lactam antibiotic, or penicillin. Make sure to pick the one with the WIDEST ZoI, because that's the one that produces most penicillin.
So now we have the root stock, but our problems have just begun. This is the part where you're absolutely going to need an alchemist's help.
The problem is that a human body is not a petri dish. It's quite a bit larger. And you want the good bacteria destroying stuff without all the nasty contaminants, so you need a SHITLOAD of mold producing a LOT of penicillin, and then you need a way to filter it. You are going to need actual lab equipment for that, or near as they had it.
Since I lost the original protocol I'm going to need to do research all over again how to do that with alchemy equipment (or at least a microbrewery), so that will be in the next installment.
Fascinating.
Concept: generic fantasy adventure where the wizard has a crackpot assistant and he explains sadly that while Hreithbert is an excellent person for keeping the wizard tower tidy and the homonculi fed they're obsessed with cooking like ten million plates of inedible goop but it makes them happy so he permits it
And at the end of the story the big reveal is Hreithbert is a time displaced biochemist who has finally fucking refined their process for penicillin.
Donβt lie, any wizard would love having ten million plates of inedible goop from their apprentice. The fact that he wonβt let you lick them is the problem.
One of the best things about being a writer is thinking of something small you can add to your work thatβs just. Devastating. Like youβre sitting there going. Oh. That would be diabolical. People would get really riled up about that. Exquisite. Letβs do it.
things in fic I'm used to people kind of faking their way through writing about:
the city of los angeles
the city of new york
sex
how drinking alcohol works
how getting high works
how a child of any age speaks
how nuclear physics work
how [my job] works
how debilitating being shot in the shoulder is
how hypothermia works
things I have never before seen someone fake their way through writing about, until today:
what french toast is
read through the notes on this one trust me
Here's some of the notes, starting with the things multiple people brought up:
SHRIMP COCKTAIL:
banahbanah: #flashback to that one fic where Peter Parker frets about drinking shrimp cocktail because of the alcohol
generaldeliciousness: adding: what a prawn/shrimp cocktail is
#why is your character turning it down because they're under 21 #do you think prawn cocktail is a cocktail #this lives in my brain rent-free constantly #the rest of the fic was so normal #and good enough that i'll still re-read it #but bro
And then many, MANY, people wondering if this was actually authour mistake, since Peter really would do this!
POMEGRANATES:
zhajhassa: #haha where's that post that was like someone describing someone eating a pomegranate but they ate it like an apple
thornhands: #once someone wrote persephone biting into a whole Pomegranate #had to stop and stare at a wall for a minute
sungsingsanguine: I once saw someone very confidently write about a character eating slices of pomegranate.
FRUIT TREES:
zagreuses-toast: #given a very endearing glimpse into a writers blindspots by seeing them describe someone sitting under a ''pineapple tree''
salatrash: I remember something about picking watermelons... OF A FUCKING TREE
baander: #cranberry trees
DOUGH/BATTER:
maycelium: #I'm a chef so I'm really used to people not accurately describing how to cook food #But I was surprisingly flabbergasted when someone was writing making a cake and was kneading it. Which uh #Not necessary for cake. It was interesting for sure but just bizarre
livebloggingmydescentintomadness: #the one that drove me nuts was when a character set aside a batch of PASTA DOUGH 'to rise' #pasta doesn't have yeast!! #it does need to REST but it will never RISE #you do not want an airy crumb on your noodles
lovesodeepandwideandwell: #THE ONE WHERE THEY MADE COOKIES BY LADLING BATTER INTO A TRAY
Some other topics:
If i were an animator for wha, i too would fall in love with brushbuddy and give it more screentime
re-watching the original trilogy is great because you really get a sense for how weird luke skywalker is, just how quickly he becomes that weird AND how quickly he commits to it. Like he's honestly pretty chill in a new hope, but the absolute INSTANT he figures out he can move shit with his mind he goes full send on the cryptic off-putting bullshit. Walking around in full black robes, speaking in riddles, aura farming and backflipping whenever physically possible. He's clearly annoyed when he first meets yoda in empire, but he dismisses that pretty quickly in favour of ALSO becoming an over-dramatic space wizard. The combination of his two teachers being yoda and obi-wan kenobi and him being the son of anakin and padme creates the single most intense and fundamentally kind force sensitive perfectly embodying the heart of the jedi order whilst also serving egregious amounts of cunt and being bizarre to be around. He would have THRIVED as a jedi master during the high republic. he would have been every padawan's favourite and every other master's worst nightmare

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let's copy papa
pulling yourself up by your strap-on or whatever they say
this is how new yorkers @ mamdani
i just feel strongly that work shouldnt be the Main Activity of five days out of the week

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I remember one time I got INSANELY high off of edibles while playing Among Us, and it quickly became apparent to the other players online. I forget how honestly but literally anything "sus" I did was ignored by everyone because I was so fucking high. I tested this theory by standing in front of a body and the person that actually reported it didn't even mention me. The funniest part was when I was trying to do wires, I kept fucking up over and over again, so I was just standing in front of wires for actual minutes trying to figure it out. A small crowd of players gathered around me to watch and would get mad every time someone reported a body or emergency meeting because "she's never going to get her tasks done if you keep interrupting them." I don't think anyone cared about winning at that point, they just wanted to see the high crew mate succeed in her tasks.
THIS IS 1000% ACCURATE LMFAO. Thank you op
Ohhhh yeah