#osteoclast

Propaganda!

An osteoclast is a type of bone cell that breaks down bone tissue. This function is critical in the maintenance, repair, and remodeling of bones of the vertebral skeleton.

Rating: M

Summary: Dick doesn’t know who’s captured him, but he does know they don’t care about his identity and they haven’t killed him. So either they need him alive for something… or they just want to hurt him.

Jason, on the other hand, knows exactly who has Dick, and why.

Warnings: Graphic Depictions of Violence

Relationships: Dick Grayson & Jason Todd

Additional Tags: Abduction, Torture, Blackmail, Hostage Situations, Electrocution, BDSM mention, Swearing, Knives, Drugging, Needles, Bloodwork, Scarecrow’s Fear Toxin (DCU), Beating, Unethical Human Experimentation, some very terrible science, Whump, unrealistic depiction of the aftereffects of electrocution, Codependency, there’s only one bed, yeah i didn’t see that one coming either but here we are, Hurt/Comfort, Gratuitous use of italics, Gen or Pre-Slash, Don’t copy to another site

This was terrible. Jason stared down at Crane's notes on the Red Hood's habits, his protectiveness of the other Bats, of Nightwing. Dick had read these notes. He was on Jason's couch right now, pretending everything was fine, while Jason sat on the floor on the other side of the coffee table and read everything Crane knew— no, presumed— about him.

"This, uh." Jason held up the copy of Crane's handwritten notes. "This isn't. I mean. This is bad science."

"Oh just wait," Dick said. He had stretched out on the couch when he'd realized Jason was going to stay on the floor, his leg propped up on some cushions. "You haven't even gotten to the methodology yet."

"I was there for that," Jason muttered.

Gut microbiota that impairs normal skeletal growth identified. Thoughts health innovators?

It is known that the human gut contains trillions of bacteria, known as the microbiota, which play a crucial role in digesting food and regulating the immune system. Gut microbiota also regulates immune processes that influence normal skeletal growth and maturation. However, the influence of specific microbes on immune-based osteoregulation is unknown. Now, a study from researchers at MUSC Health…

Week Seven: Tuesday, February 26, 2019

Reading week was last week and marked the halfway point of the semester and also a slight change in direction of lecture content. Up until now, lectures have been focused on different things that effect biological anthropology but this second half of the semester has switched over to focus more on the different subfields of biological anthropology.

This week we focused in on the subfield of human osteology and paleopathology, basically the study of the human skeleton. We first talked about the osteoblasts, osteoclasts, and osteocytes that make up bone cells and their roles; osteoblasts making new bone and repairing the old, osteoclasts breaking down of old bone, and osteocytes being inactive osteoblasts that are trapped in the bone matrix. We then went on to talk about what exactly bones do aside from hold humans and animals together, this was separated into three subcategories; mechanical, synthesizing and metabolic. Mechanically bones protect organs and allow for tissue attachment, bones also produce red and white blood cells as well as platelets, and they are also where minerals, calcium, and good fats get stored.

Crossed Bones

Cancers that spread to bones are often difficult to treat, but finding out how tumour and bone cells live side by side may help to heal osteolytic lesions – tears created in bone tissue as a tumour grows inside. Intravital microscopy watches as this lesion, in mouse bone, widens over several days. From blue to green to red – consecutive overlapping pictures show the fringe of the hole eaten away by bone resorption – when bone cells are broken down. This bone tissue was actually grown in a lab under a mouse’s skin, with a thin surface ideal for peering through. Treating the lesion with a chemical called zoledronic acid slows the bone’s deterioration – just as it does in human patients – but doesn’t stop the cancer growing. Using biological models like this, scientists can now test combinations of drugs that preserve the bone, while targeting the cancer cells inside.

Written by John Ankers

Image by Eleonora Dondossola and Peter Friedl, MD Anderson Cancer Center

David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Image copyright held by the original authors

Research published in Science Translational Medicine, August 2018

Backscattered electron scanning electron microscope image showing osteoclast resorption of trabecular bone (roughened surfaces). The osteocyte lacunae and canaliculi are also seen within the trabeculae.

Rating: M

Summary: Dick doesn’t know who’s captured him, but he does know they don’t care about his identity and they haven’t killed him. So either they need him alive for something… or they just want to hurt him.

Jason, on the other hand, knows exactly who has Dick, and why.

Warnings: Graphic Depictions of Violence

Relationships: Dick Grayson & Jason Todd

Additional Tags: Abduction, Torture, Blackmail, Hostage Situations, Electrocution, BDSM mention, Swearing, Knives, Drugging, Needles, Bloodwork, Scarecrow’s Fear Toxin (DCU), Beating, Unethical Human Experimentation, some very terrible science, Whump, unrealistic depiction of the aftereffects of electrocution, Codependency, there’s only one bed, yeah i didn’t see that one coming either but here we are, Hurt/Comfort, Gratuitous use of italics, Gen or Pre-Slash, Don’t copy to another site

Dick was alive. He was pretty sure, anyway. Less certain was his lucidity, but the fact that he was wondering about that was probably a sign that he was well on his way there.

He hurt. All over. From the electrocution and stabbing, yeah, but also from struggling so hard after being injected with what he now realized, now that the effects had passed, was fear toxin.

So. That answered the lingering question he'd had about who was behind this. Scarecrow, almost certainly. The why was still a bit of a mystery.

The door to his cell opened and a snarl scrawled itself across Dick's face without his permission. They'd ignored him for such a long time, and now two visits this close together? Or – were they close together? How long had he been out? What had happened? What did they want? Whatever it was, he was out of quippy sarcasm for whichever goon was paying him a visit now.

But it was only medical student David, bearing his bag of supplies. The door clanged closed behind him and he jumped, flung a skittish look at the camera, and scuttled over to Dick, stopping short – but still well within kicking distance.

"Um. Don't kick me, okay?" David said.

"Glad to see you're still alive," Dick said. He made no promises about the kicking, but David seemed to think he had because he came closer.

"For the moment," David muttered, too quietly for the camera to pick up. He knelt beside Dick, keeping his back to the steady red eye in the corner. "They want me to sedate you so I can treat your injuries," he said, voice barely audible even this close. He showed Dick a syringe while making a show of checking his wounds.

"If you think I can't manage a triangle choke like this, you would be wrong," Dick said, letting the growl into his voice.