Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions between organelles are important for regulating cellular processes.  Inside every eukaryotic cell lies a vast and dynamic network known as the ER. Stretching through the cytoplasm, this intricate…

Study in mice shows that the endoplasmic reticulum stress response helps tamp down brain activity — ScienceDaily

In response to seizures, the endoplasmic reticulum (ER), a network of flattened tubes in the cell that packages and transports proteins, triggers a stress response that reduces brain activity and seizure severity. The new findings, reported by Nien-Pei Tsai and colleagues at University of Illinois at Urbana-Champaign on 26th September in PLOS Genetics, may have important implications for the…