#bioprint

The health industry has undergone incredible technical advancements during the past decade.

The pandemic gave the pharmaceutical industry the chance to use more technology than ever before, driving the sector's digitalization and influencing how pharma will function in the future.

Such revolutionary advancements have had a positive effect on the pharmaceutical sector and its products. 

Industry experts have named technologies such as AI and big data as the top technologies that will revolutionize and adapt pharmaceutical drug research and development processes. 

Let's have a look at what exactly is the pharmaceutical industry advancing through technology and which ones are leading in the advancement:

Big Data Big Data is a body of information that is large in volume and is always expanding exponentially. Due to its size and complexity, no traditional data management system can store or process this data adequately. Big data is a category of extraordinarily huge data.

The structuring and streamlining of information is a top goal for many pharmaceutical industries due to the large amount of data being produced from various sources. Big data has a huge positive impact on drug invention, clinical trial procedures, R&D expenses and fields like marketing and sales.

Improved methods for drug discovery and development With so many potential uses, for some time now, artificial intelligence has been a popular matter in the pharmaceutical industry and the list of potential applications for AI in pharma has only grown over time.

AI is expected to continue to have a favorable impact on the pharmaceutical industry as a whole. AI is speeding the rate at which pharmaceutical industries will discover new medical care options and processes.

3D printing As 3D printing gains popularity, there have been discussions about its use to create printed organs using bioprinters that could be used for transplants. Many have predicted that this may advance significantly over the next five years, though this would depend on how quickly printed organs can be produced.

New manufacturing techniques The sector is now discovering new technologically-assisted manufacturing methods, including as small batches for precision medicine, as a result of changed market dynamics.

For example,single-use bioreactors are becoming more popular.

because they significantly reduce downtime and increase productivity.

It is possible to improve medication discovery and development procedures by using technology, which will ultimately be more economical and effective in the long run.

Pharmaceutical companies will only continue to develop and pave new ground as new technology like 3D printing is applied to the industry.

3D printing of the human heart

A printable organs is an artificially designed device intended to replace organs made using 3D printing techniques. The main use of pressure organs is in transplants. At present, research is being carried out on the artificial structures of the heart, kidneys and liver, and in other important organs.

For more complex organs, such as the heart, smaller structures such as heart valves have been…

3D printed heart projects of 2018 (continued)

3D bioprinting is the use of the additive manufacturing techniques that combine cells, compounds and biomaterials to create tissue-like structures used in medical and tissue engineering. Unlike traditional FDM 3D printing, which uses filament or plastic, bioprinting uses “bioink”, which is a mixture of biomaterials and cells.

As you can imagine, this technology is massively important for the medical industry. Its primary use would be to save the lives of the millions of patients who are in need of a replacement organ or transplant. As it stands, around 20 people die every day in the United States waiting for a replacement organ. To make things worse, host rejection of the organ eventually requires another replacement. Being able to 3D print artificial organs using patients own cells can eliminate this major deficit in the transplant industry.

2. Wake Forest Institute for Regenerative Medicine

Dr. Anthony Atala, the director of the Wake Forest Institute for Regenerative Medicine is a huge name in the field of 3D bioprinting. His team has already successfully engineered and transplanted bladders into living patients. In April 2018, they further published a paper describing how they 3D bioprinted functional and contractile cardiac tissue using rat heart cells.

The cells were suspended in bioink and printed into precise structures. This allowed for the cardiac cells to align into an organized structure similar to human heart tissue. Dr. Atala and his colleagues were even able to test the effects of adrenaline, which increases heart rate, and carbachol, which lowers heart rate. They found that both drugs resulted in the expected change of heart rate.

However, just like Biolife4D’s heart patch, there is still a lot of work to do before we get to a full-sized functional and vascularised 3D printed heart.

3. Artificial Silicone Heart

Although not bioprinted, in 2017 a team of researchers from Switzerland published a paper describing the development of a fully functionally beating heart 3D printed in silicone. Roughly the same size as a human heart and imitating the same function, their work demonstrates how we’re quickly approaching the ability to replace hearts without the need for transplants.

New 3D Bioprint Technique May Help Replace Damaged Tissue

New bioprint tubular structures that resemble native vessels and ducts in the body is discovered by a research team. This 3D bioprinting method may offer potential viable replacements for damaged tissue, reports a new study. The findings of the study are published in the journal Advanced Materials.

“The vessels in the body are not uniform,” said Yu Shrike Zhang, Ph.D., senior author on the…