Science this beard!

It’s me, Tyrone, again. –> @tyronerodriguez I’ve taken over duties with today’s megapost, which was supposed to go live last week #sorry. We were busy updating the PC version and announcing the Nintendo Switch retail version of The Binding of Isaac: Afterbirth+. Oh yeah, we also released Rebirth on iOS. It was a busy week.

AFTERBIRTH+ STATUS REPORT If you’ve played Afterbirth+, you’ve probably seen the regular patches, bug fixes and tweaks since launch. It’s been just over two weeks since launch and we’re still working away at making sure the game is perfect, as-balanced-as-possible and as bug-free as possible. If you’re having issues getting the game running, I apologize and we’re probably either working on a fix and/or there might already be one available. Some of you put together a collective bug list, thank you for that–you’re really awesome: https://docs.google.com/document/d/1AVAvmAgN_ioU-rrvTkTTmk4wRckAb4zXho_3V0Gb2T0/edit#heading=h.254nqn55vs0c If you have anything to report please send it (and be as thorough as possible) to [email protected]

tl;dr We’re still fixing stuff, we’ll continue to fix stuff and we are still accepting/considering feedback that will improve the game experience BOOSTER PACKS We’re still committed to providing updates as long as there’s new content created by the community. You’ve already been busy making really great items, weapons and mods for the game. We’ll will have an official method of submissions and accepting mods into monthly updates. Keep doing what you’ve been doing. Personally, I’d love to put in @ThatScayze’s Pac-Man Mod, as a random bonus room.

API/MOD SUPPORT When we started working on mod support and opening up the game to all of you, I was very hopeful that you’d make amazing things. As I mentioned previously, tomorrow will be two weeks since launch and you’ve already impressed the entire team with what you’ve created in such a short amount of time. I can’t imagine what you will be making a year from now. Like the main portion of AB+, we’re still fixing bugs, updating the API and making improvements that will allow you to make more changes to the game. What you see now isn’t the final version of the mod tools, but just the beginning. If you do have feature requests, also send them to [email protected] with subject: Mod Tools Suggestion

Later this week/early next week we plan to do a quick Mod Tools Tutorial stream online with a few of the Afterbirth+ team members to help you get a better understanding on how to get started modding. Watch my Twitter @tyronerodriguez for more details as we get ready to confirm a final date and time. We’ll also be fielding questions from the chat during the tutorial stream.

iOS The Binding of Isaac: Rebirth is available on iOS as a universal binary. We’ll have AppleTV support at a later time, but right now it’s touch- and MFI-compatible. Requires iOS10, runs at 60fps xoxo

You can report iOS bugs to [email protected]; please put iOS Isaac Bugs in the subjectline.  We’re investigating a few things, including keyboard support. If you have any other feedback or reasonable requests, I’m listening. For unreasonable requests, please see Northernlion.

Other stuff..

NINTENDO SWITCH By now you’ve hopefully heard that The Binding of Isaac: Afterbirth+ is coming to Nintendo Switch in retail form. What does it mean?

It means that there is more than just The Legend of Zelda: Breath of the Wild on launch. Afterbirth+ will be available at retail as well as on the Nintendo eShop for $39.99 and will include Rebirth, Afterbirth and Afterbirth+ packed together as one game.

If you’re that excited about the game, it’s still available to pre-order at GameStop and Amazon. You might want to consider pre-ordering as the first few thousand copies may come backed in with something special Amazon: http://a.co/9MKriNl Gamestop: http://www.gamestop.com/games/binding-of-isaac-afterbirth-nintendo-switch/141924 You can also get our other Switch game, Redout out, too: Amazon: http://a.co/i8NY8Ss Gamestop: http://www.gamestop.com/games/redout-nintendo-switch/141922 Bye! ༼ つ ◕_◕ ༽つ PRAISE NICOLO ༼ つ ◕_◕ ༽つ

Fire Emblem Gaiden remake coming to 3DS ⊟ 

25 years after releasing for the Famicom in Japan (and nowhere else), Fire Emblem Gaiden is finally coming to the rest of the world with a 3DS remake! Fire Emblem Echoes: Shadows of Valentia completely overhauls the original an Awakening/Fates-style look, animated cutscenes by Khara, Inc. (Rebuild of Evangelion), voice acting, and all other presentation elements.

A two-pack of amiibo figures for Shadows of Valentia’s hero and heroine, Alm and Celica, will release alongside the game on May 19.

No really

You won’t believe what kind of heart this surgeon has been feeding his party guests!

This cannibal feeds human sausages to a dog. What happens next will warm your heart

Find out the bizarre reason this doctor keeps a plastic suit in his closet!

Unique microbial photosynthesis discovered: Finding could be used for waste treatment, energy

Researchers at Washington State University have discovered a new type of cooperative photosynthesis that could be used in engineering microbial communities for waste treatment and bioenergy production.

They report today on the unique metabolic process seen for the first time in a pair of bacteria in Nature Communications.

Photosynthetic bacteria account for nearly half of the world’s food production and carbon-based organic material. The research could also improve understanding of lake ecology.Researchers at Washington State University have discovered a new type of cooperative photosynthesis that could be used in engineering microbial communities for waste treatment and bioenergy production.They report today on the unique metabolic process seen for the first time in a pair of bacteria in Nature Communications.Photosynthetic bacteria account for nearly half of the world’s food production and carbon-based organic material. The research could also improve understanding of lake ecology.

Phuc T. Ha, Stephen R. Lindemann, Liang Shi, Alice C. Dohnalkova, James K. Fredrickson, Michael T. Madigan, Haluk Beyenal. Syntrophic anaerobic photosynthesis via direct interspecies electron transfer. Nature Communications, 2017; 8: 13924 DOI: 10.1038/NCOMMS13924

How clever!

Natural tooth repair method, using Alzheimer’s drug, could revolutionize dental treatments

A new method of stimulating the renewal of living stem cells in tooth pulp using an Alzheimer’s drug has been discovered by a team of researchers at King’s College London.                                

Following trauma or an infection, the inner, soft pulp of a tooth can become exposed and infected. In order to protect the tooth from infection, a thin band of dentine is naturally produced and this seals the tooth pulp, but it is insufficient to effectively repair large cavities.

Currently dentists use man-made cements or fillings, such as calcium and silicon-based products, to treat these larger cavities and fill holes in teeth. This cement remains in the tooth and fails to disintegrate, meaning that the normal mineral level of the tooth is never completely restored.

However, in a paper published today in Scientific Reports, scientists from the Dental Institute at King’s College London have proven a way to stimulate the stem cells contained in the pulp of the tooth and generate new dentine - the mineralised material that protects the tooth - in large cavities, potentially reducing the need for fillings or cements.