I know gohime is popular because of her endless suffering at the hands of that annoying teenager, and people like to read that over the top animosity as something else. A cover for something else, but I would like to propose suguhime.
While utahime fucking satoru despite his general unpleasantness is fun and all, suguru and utahime fucking is even more meaty to me because suguru has that same kind of meanness in him, but he's also a lot more cunning about it. He knows he can get that cookie, and he does despite being just as bad because he knows how to make himself likeable. And it's even better for the satoru&utahime dynamic because he's the annoying, unhelpful, smartass friend of the guy she's fucking and she just has to suffer through it for suguru's sake. It makes their fights more fun to me.