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MERU, a Phase 3 placebo-controlled trial evaluating Rova-T as a first-line maintenance therapy for advanced small-cell lung cancer (SCLC), demonstrated no survival benefit for patients receiving Rova-T at the interim analysis – Independent Data Monitoring Committee recommended terminating the study due to lack of survival benefit

AbbVie (NYSE: ABBV), a research based global biopharmaceutical company,announced that MERU, a Phase 3 trial evaluating Rova-T as a first-line maintenance therapy for advanced small-cell lung cancer (SCLC), demonstrated no survival benefit at a pre-planned interim analysis for patients receiving Rova-T as compared with placebo. The overall safety profile was generally consistent with that observed in previous studies. The MERU trial is being closed, and the Rova-T research and development program has been terminated. AbbVie will move forward prioritizing other development programs within its oncology pipeline.

An Independent Data Monitoring Committee (IDMC) recommended terminating MERU due to lack of survival benefit for patients receiving Rova-T compared with the placebo control arm based on results at a pre-planned interim analysis. Results from the MERU trial will be presented at a future medical meeting and/or published in a peer-reviewed medical journal.

“Siemens Healthineers continues to position itself as a leading company for providing vocational training. That’s why we’re investing in up-to-date training facilities and expanding our capacity. It’s a clear commitment to leadership in innovation and to Erlangen as a business location,” says André Heinz, head of Human Resources at Siemens Healthineers.

Group sales increase by 0.9 percent (Fx & portfolio adj.) to 11.485 billion euros / EBITDA before special items advances by 24.7 percent to 2.927 billion euros / Crop Science sees sales decline (Fx & portfolio adj. and pro forma) in challenging environment but posts substantial earnings growth due to acquired business / Pharmaceuticals posts higher sales and strong earnings growth / Consumer Health increases sales and earnings / Net income falls by 49.1 percent to 404 million euros, held back by special items for restructuring and impairments / Core earnings per share increase by 5.9 percent to 1.62 euros / Group outlook confirmed yet increasingly ambitious

The Bayer Group continued to grow in the second quarter of 2019. “Bayer is on track in its operational business,” said Werner Baumann, Chairman of the Board of Management, when presenting the half-year financial report on Tuesday. “Sales at Crop Science were primarily held back by the extreme weather conditions in North America, while at Pharmaceuticals we recorded encouraging growth,” he said. Business was also up at the Consumer Health Division. Baumann confirmed the Group outlook for 2019, but noted that it was becoming increasingly ambitious.

Sales of the Bayer Group rose by 0.9 percent on a currency- and portfolio-adjusted basis (Fx & portfolio adj.) to 11.485 billion euros in the second quarter. On a reported basis, sales were up by a substantial 21.1 percent. EBITDA before special items increased by 24.7 percent to 2.927 billion euros. Negative currency effects arising primarily from hedging diminished earnings by 59 million euros compared with the previous year. EBIT declined by 31.2 percent to 926 million euros after net special charges of 859 million euros (Q2 2018: 362 million euros). The special charges mainly comprised impairment losses in connection with the agreed divestment of Dr. Scholl’s™ and expenses related to the announced restructuring measures.

Net income declined by 49.1 percent to 404 million euros. By contrast, core earnings per share from continuing operations rose by 5.9 percent to 1.62 euros. Free cash flow amounted to 751 million euros, down by 60.8 percent. This significant decline is due to the seasonality of the newly acquired Crop Science business. Since the acquisition closed in June 2018, the high cash outflows in April and May 2018 were not taken into account. Net financial debt as of June 30, 2019, increased to 38.808 billion euros, up 5.6 percent from March 31, 2019, due mainly to the dividend payment.

Crop Science impacted by extreme weather conditions

In the agriculture business (Crop Science), Bayer generated sales of 4.788 billion euros. On a reported basis, sales were up by 59.0 percent, thanks mainly to the acquisition of Monsanto. Overall, business at Crop Science in the second quarter was significantly impacted by extreme weather conditions. In particular, flooding and heavy rains in the Midwestern United States and drought in large parts of Europe and in Canada had a negative effect. Ongoing trade disputes also weighed on business. Sales were down by 3.1 percent after adjusting for currency and portfolio effects, with the development of the acquired business only taken into account for the period June 7 to June 30. This decline was mainly the result of a considerable drop in sales in North America. Significant sales gains in Latin America did not offset this effect.

On a pro-forma basis, sales of Crop Science declined by a currency-adjusted (Fx adj.) 9.9 percent. In this context, sales are presented as if the acquisition of Monsanto and the associated divestments had already taken place as of January 1, 2018. On this basis, business was down at Soybean Seed & Traits, Herbicides and Corn Seed & Traits in particular. By contrast, sales increased at Insecticides.

EBITDA before special items of Crop Science rose by 66.9 percent to 1.075 billion euros. The increase was largely attributable to the earnings contribution from the acquired business. Earnings were diminished by the decline in sales, the absence of the earnings contribution from the businesses divested to BASF, inventory write-downs and a negative currency effect of 26 million euros.

Canicule, soleil : les parents n’auraient pas les bons réflexes pour protéger leurs enfants du soleil…

90,37% des parents n’appliquent pas au bon moment la crème solaire à leur bambin. Ils sont encore 21,34% à penser que les crèmes écran total existent vraiment. Ils sont aussi 34,61% à promener leur bébé entre 11h et 16h, aux heures les plus chaudes et dangereuses de la journée !

Pas étonnant dès lors que 39,88% des enfants de moins de trois ans aient déjà eu des coups de soleil. À répétition, ces…

  But while we are at it, we should never forget to give our skin the Tender loving care she deserves. For this reason, I will be introducing you to the products I use this summer which was a gift from the best multinational online pharmacy widely famous for selling quality cosmetics, vitamins, beauty products and non prescription drugs : NEWPHARMA

Few days ago, I received a summer box from Newpharma and the box contained 9 lovely products which have become my summer holy grail. These products were selected specifically for my skin type and I am happy to announce to you that they have products for ALL skin types and very affordable as well.

  MY SUMMER BEAUTY PRODUCTS 

Micellar water from Eucerin

  This product is a necessity for all ladies because it contains some cleansing properties which helps to remove every trace of makeup from your face without drying out or irritating your skin. So instead of using make up removal pads which are always scented and dry out the face afterwards, why not invest in this product? I used this cleansing fluid to get rid of my makeup on Friday night and I was wowed with how moisturized and clean my face felt afterwards. Get yours here.

Last Friday in Edenkoben, Rheinland Pfaly Germany.

  Shower gel from La Roche-Posay 

I noticed that little goes a long way with this shower gel. It lathers so well and the smell on the other hand is heavenly! This shower gel is ‘dope’ and I will give it a 5 star rating because the fragrance lingers for a long time. Who needs a perfume after using La Roche- Posay? Get one tube at a discounted price here.

   Deodorant from Rogé Cavaillès 

  I can confidently say this without bating my eyelids: ‘THIS IS NOT YOUR REGULAR DEODORANT’. Roge Cavailles Dermato deodorant is one of the products that when your discover, you cant help but give it glowing reviews. This deodorant contains no aluminium and when I sprayed this under my armpit, I noticed that it didn’t streak down, rather it dried up immediately.

The downside is minimal white patches under my armpit, but it is barely noticeable. This is a perfect gift idea for your girlfriends or sisters this summer and the packaging is so luxurious. Get yours here.

    Cleansing gel from Uriage  

I have a love/hate feeling with this cleansing gel. It really purified my skin and gave me a ‘clean’ feeling but, I noticed that it dried out my skin afterwards. However, I think it will benefit people with oily skin so much , but please make sure you use a serum or moisturizer afterwards. I used the Vichy 89 moisturizer afterwards and my face felt so soft and fresh. Click here to get yours.

 Thermal water spray from Vichy 

I was skeptical at first because I had never used Thermal water before, but this is now my holy grail. As a girl with acne-prone skin, I was worried that the 15 minerals in this thermal water will give me fresh breakouts, but I was wrong. It made my skin softer and keeps breakouts at bay.

I use it before applying my Vichy 89 moisturizer and also before applying my makeup. It sets the makeup up so well and it is very refreshing to the skin especially when it is refrigerated. I love this product and I will recommend to everyone regardless of your skin type.  Always make sure you seal in the moisture afterwards with Vichy serum. Get yours here.

  Moisturising booster from Vichy

This product has very high concentration of Vichy Thermal mineralizing water. Vichy Mineral 89 is a combination of serum and moisturizer in one tube. I love this product because it is non- greasy and very lightweight. It contains NO oil, parabens, alcohol, fragrance etc. Infact, what you see is what you get. This product is suitable for all skin types and I have nothing bad to say about it. Get yours here.

  Anti dark circles care product from Remescar 

My husband and I used this product together and I can say that this anti dark circles cream works like magic. It makes all your dark circles disappear in less than 2 minutes. Remescar anti dark circle cream tightens, brightens and fades wrinkles in your eyes region. Splurge on this eye cream now and thank me later!

I usually apply eye cream with my pinky finger because the eye area is so delicate and using the thumb or the index finger might exert lots of pressure on the region. The downsides includes:

1. It leaves chalky residue when the product dries off.

2. It contains so little product and is somewhat expensive but then, little goes a long way.

This is a perfect gift idea for your friends and even parents who have bags under their eyes. Check it out here.

  Also, I received Sample moisturizing cream from Clinique and Sample body lotion from Château Rouge.

I am not really gushing over these products because I got them for free because I wouldn’t endorse anything if they don’t work. So if you really want a ‘Beyonce’ skin (a very supple and clear skin) then visit NEWPHARMA.DE  and please don’t forget to share your experience with me (whether good or bad).

Please let me know your thoughts below.

Thank you NEWPHARMA.DE  for these gifts

Visit www.newpharma.de to buy your original skin products!

Wie wird sich die Rolle des Pharma Außendiensts in Zukunft verändern und wie wird dadurch die Interaktion mit dem Healthcare Professional (HCP) beeinflusst?

http://www.otto-company.com/pdf/OandC_SalesForceOfTheFuture

Apaisac Biorga : le bon plan pour les peaux sèches !

Parce que les peaux sèches et sensibilisées sont constamment mises à l’épreuve, elles méritent d’être chouchoutées encore plus que les autres.  La gamme Apaisac Biorga des Laboratoires Bailleul devrait aider ces peaux atopiques à enfin retrouver leur douceur d’antan.  (more…)

Newpharma kortingscode november 2015

[coupons store=”newpharma” limit=”10″ orderby=”date” order=”DESC”]   Voorwaarden kortingscode Newpharma.nl Deze kortingscode is geldig bij uw bestelling vanaf €25, uitgezonderd geneesmiddelen. U kunt de kortingscode niet gebruiken in combinatie met andere kortingscodes, maar wel met voorwaarden voor gratis levering. U kunt deze speciale Newpharma.nl kortingscode slechts 1 keer gebruiken.