#melanopsin

As I scanned through my email boxes to clear out space I noticed my set of emails from when I worked in a lab during my first master's, the emails were a conversation between myself and several scientific journals when I was trying to publish my first paper. One journal said it was too biological, another said it was too engineering-based, another journal said it was too biophysical, and a fourth journal said it was too bio and optics based. The paper covered the circadian rhythm, creations of technology related to circadian entrainment, and a proposition of a new piece of tech, one also with the goal to entrain the eyes, thereby the circadian system, to make people feel more sleepy. I noticed that one journal had only two reviewers, the chief editor and someone handpicked by them, and the handpicked individual said "melanopsin is not a photoreceptor".... melanopsin is a photoreceptor expressed by GPCRs, and preferential responds to blue light at 480nm and wavelengths of light of similar lengths close to that number, but 480 is best to get them to respond.

I say this because, please, keep in mind that even the educated people that you may speak to are utterly nonsensical, they have no mensa, there's nothing, not even emptiness inside their heads. Furthermore, the chief editor stated that it was unfair for me to reference a paper they allowed to be published in their journal from 2009, claiming that "things change in science so it isn't fair to make comparisons"; trust me, I'm perhaps the only person who has an astounding understanding that things change, especially in science.

“It’s a] strong demonstration that opsin-dependent photoreceptors in deep brain areas affect behaviors,” 

or light/dark sensitive cells that communicate with the SCN

Via https://bigpictureeducation.com/proteins-eye

“The cells here undergo a cycle of protein formation and breakdown that lasts around 24 hours, releasing chemicals that make us sleepy at night and awake during the day. This cycle can be modified by input from melanopsin cells, which tell the SCN when it is light (daytime).

One way this is done is through melatonin (not to be confused with melanopsin). Melatonin is a hormone that makes you feel sleepy. It is produced by the pineal gland, connected to the SCN, which receives the light/dark signals from the melanopsin cells in the eye.

So when the melanopsin cells detect light (normally in the daytime), less melatonin is produced, making you feel more awake. When it is dark and melanopsin cells don’t detect light, more melatonin is produced, making you feel tired.

Melanopsin is most sensitive to blue light. This is why it’s a bad idea to be on your phone or computer late at night: these devices give out a lot of blue light, which the melanopsin detects as bright daylight. This tells your body clock that it is daytime and you should be awake, stopping you from getting to sleep.

“SUNRISE, SUNSET, SUNRISE, SUNSET, SWIFTLY FLY THE YEARS

آیا می دانستید که نور سبز و نور آبی در تنظیم خواب نقشی اساسی دارند؟ دستگاه های نور درمانی خانگی یکی از منابعی است که می تواند در تنظیم خواب تاثیر مثبت داشته باشد. اما آیا همه دستگاه های نور درمانی چنین عملکردی را از خود بروز می دهند؟

مقدمه

تحقیقات نشان داده است که در زندگی ما، نور سفید، در لامپ های روشنایی باشد یا نور خورشید، یا دستگاه های نور درمانی خانگی دارای طیف های مختلفی است. یعنی یک رنگین…

The muscles contolling the shape of the Iris (and consequently the pupil) in cat's eyes do not rely on nerve signals, instead they use the light-sensative puigment melanopsin. It means that even when disconnected from the brain, the iris still reacts to different levels of light.