#hypoxemia

Hypoxemia with an increased A-a gradient

A-a gradient (normal) = 5-10 mmHg ・Medically significant A-a >30 mmHg

PᴀO₂ = %O₂ (713) - PaCO₂/0.8 ≈ 150 - PaCO₂/0.8

↑A-a gradient : ↓PaO₂ of pulmonary origin

Ventilation defect ➝ Impaired O₂ delivery to alveoli ・Oxygen supplementation does not improve PaO₂ if diffuse airway collapse ・Produces intrapulmonary shunt ・Ex: airway collapse (atelectasis) due to RDS, mucus plug

Perfusion defect ➝ Increased pathologic dead space ・Oxygen supplementation does improve PaO₂ ・Ex: pulmonary embolus

Diffusion defect ➝ O₂ cannot diffuse through alveolar-capillary interface ・Ex: interstitial fibrosis, pulmonary edema

Monitoring 2 signs easily measured at home can cut COVID death risk

New York: Simply monitoring respiration rate and blood-oxygen saturation at home can cut the risk of death due to COVID-19, finds a study. According to the current guidance from the US Centers for Disease Control and Prevention (CDC), people with COVID-19 must seek medical attention when they experience overt symptoms such as “trouble breathing” and “persistent pain or pressure in the chest” —…

ينقل الدم الأكسجين إلى أعضاء وأنسجة جسمك. ويحدث نقص الأكسجين بالدم – Hypoxemia بسبب مجموعة متنوعة من الحالات، بما في ذلك الربو والالتهاب الرئوي ومرض الانسداد الرئوي المزمن (COPD)، وهى حالة طبية خطيرة وتتطلب عناية طبية فورية. (more…)