Cable 81 was published with a cover date of July 2000. It was a multiverse issue that also involved Earth-22073 and Earth-2775. The issue saw the deaths of Blockade (Dexter Parrish) and Henry Oxton. ("The Nexus of Time and Space", Cable 81, Marvel Comic Event)

Cable 78 was published with a cover date of April 2000. The issue introduced the Ranshi Empire (Sandella Ranshi, Holdyne, Malan, and Kriven) and the time-ship Conquest created by Joe Pruett and Michael Ryan. ("I still Believe I Cannot Be Saved", Cable 78, Marvel Comic Event)