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RNA Interference
Introduction RNAi was discovered by Andrew Fire and Craig Mello via an experiment on gene expression in Caenorhabditis elegans, in which they injected mRNA (also known as sense sequence) coding for muscle protein production showed no response form c. elegans. From this, they tried injecting anti-sense RNA to pair with sense mRNA, and yet no response was elicited. Eventually they chose to inject…
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Biologists first to observe direct inheritance of gene-silencing RNA
Recent research has shown that, in some species, parents' life experiences can alter their offspring DNA. However, the mechanisms that cause this effect—known as non-genetic inheritance—are a mystery.
New research from the University of Maryland provides a surprising possible explanation. For the first time, developmental biologists have observed molecules of double-stranded RNA (dsRNA) being passed directly from parent to offspring in the roundworm Caenorhabditis elegans. Importantly, the gene silencing effect created by dsRNA molecules in parents also persisted in their offspring.
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(via https://www.youtube.com/watch?v=JFnqvPptcEc)
The question that serious scientists are asking is: If we (or bees, or birds, or deer) consume the dsRNA in the apple or potato, can it influence how our genes work? Will these genetically modified organisms (GMOs), eaten as apple pies, french fries, or whatever, change our development, physiology, and behavior?
