“ It was observed, and I could give several instances within the compass of my own knowledge, where a servant had been taken sick, and the family had either time to send him out or retire from the house and leave the sick person, as I have said above, they had all been preserved; whereas when, upon one or more sickening in a family, the house has been shut up, the whole family have perished, and the bearers been obliged to go in to fetch out the dead bodies, not being able to bring them to the door, and at last none left to do it.
This put it out of question to me, that the calamity was spread by infection; that is to say, by some certain steams or fumes, which the physicians call effluvia, by the breath, or by the sweat, or by the stench of the sores of the sick persons, or some other way, perhaps, beyond even the reach of the physicians themselves, which effluvia affected the sound who came within certain distances of the sick, immediately penetrating the vital parts of the said sound persons, putting their blood into an immediate ferment, and agitating their spirits to that degree which it was found they were agitated; and so those newly infected persons communicated it in the same manner to others. And this I shall give some instances of, that cannot but convince those who seriously consider it; and I cannot but with some wonder find some people, now the contagion is over, talk of its being an immediate stroke from Heaven, without the agency of means, having commission to strike this and that particular person, and none other—which I look upon with contempt as the effect of manifest ignorance and enthusiasm; likewise the opinion of others, who talk of infection being carried on by the air only, by carrying with it vast numbers of insects and invisible creatures, who enter into the body with the breath, or even at the pores with the air, and there generate or emit most acute poisons, or poisonous ovae or eggs, which mingle themselves with the blood, and so infect the body: a discourse full of learned simplicity, and manifested to be so by universal experience; but I shall say more to this case in its order. “
Daniel Defoe, A Journal of the Plague Year, Dover Publications, Inc., Mineola, New York, USA, 2001; page 57.
[ Original Edition: E. Nutt, London, United Kingdom, 1722 ]
