#antigen processing and presentation

Competing interests R.G.J. reports consultancy fees in past three years from: AbbVie, AdAlta, Apollo Therapeutics, Arda Therapeutics, Astra Zeneca, Bristol Myers Squibb, Chiesi, Cohbar, Contineum Therapeutics, Galecto, GlaxoSmithKline, Mediar Therapeutics, Ono, Orion, RedX, Syndax, Pliant and PureTech; and lecture fees from: AstraZeneca, Boehringer Ingelheim, Chiesi, Gilead and Roche. He is…

Nature Immunology, Published online: 02 January 2026; doi:10.1038/s41590-025-02367-5 New data show that DNGR-1 enables type 1 conventional dendritic cells to sculpt cancer immunoediting through selective cross-presentation of F-actin-tethered neoantigens, enriching tumors for immune-evasive variants. Read more about this post… Credits: Source Disclaimer

Antibodies, plasmids and reagents Western blot analyses were performed using primary antibodies at a dilution of 1:1,000 unless otherwise specified. Anti-STAT1 (D1K9Y, 14994), anti-STAT2 (D9J7L, 72604), anti-STAT3 (Rabbit, 79D7, 4904; Mouse, 124H6, 9139), anti-STAT4 (C46B10, 2653), anti-STAT5 (D2O6Y, 94205), anti-STAT6 (D3H4, 5397), anti-JAK1 (6G4, 3344), anti-JAK2 (D2E12, 3230), anti-JAK3…

Structure/Function Studies of Antigen Processing and Presentation The intricate process of antigen processing and presentation is fundamental to the immune response, enabling the recognition of a vast array of pathogens by T cells. This process is primarily mediated by major histocompatibility complex (MHC) molecules, which present peptide antigens on the surfaces of cells. Structure/function…