half agony, half hope @paramores - Tumblr Blog

tv shows used to have hot guys and by hot guys i mean chad michael murray

#you will never gaslight me into believing nathan was the hotter brother on oth #'lucas was a pos blah blah blah' ok and? that was cmm's pretty face on my screen #also lucas and peyton for ever idgaf!!!!!!!!#ignore me

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macgyvermedical

When Drugs Became Available

Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:

Acetaminophen: 1950

Albuterol: 1969 (UK) 1982 (US)

Allopurinol: 1966

Alprazolam: 1981

Amitriptyline: 1961

Amlodipine: 1990

Amoxicilin: 1972

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Apixiban: 2012

Aripiprazole: 2002

Aspirin (first NSAID): 1899

Azidothymidine (first antiviral): 1987

Barbital (first barbiturate): 1903

Bupropion: 1985

Buspirone: 1986

Calcium Carbonate (TUMS): 1930

Captopril (first ACE inhibitor): 1981

Chlordiazepoxide (first benzodiazepine): 1960

Chlorothiazide (first thiazide diuretic): 1957

Chlorpromazine (first antipsychotic): 1952

Cyclobenzeprine: 1977

Diphenhydramine: 1946

Furosemide: 1959

Fluoxetine (first SSRI): 1988

Gabapentin: 1993

Glipizide: 1984

Hydrochlorothiazide: 1959

Ibuprofen: 1969 (UK) 1974 (US)

Insulin: 1923 (though many types of insulins would become available over the next century)

Imipramine (first tricyclic antidepressant): 1959

Iproniazid (first antidepressant (MAOI)): 1952

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Lisinopril: 1987

Lithium: 1949

Losartan (first ARB): 1995

Lovastatin (first statin): 1987

Naproxen: 1976 (Rx) 1990 (OTC)

Nitrogen Mustard (first chemotherapy agent): early 1940's

Methotrexate: 1947

Methylphenidate: 1954

Metformin: 1957 (France) 1995 (US)

Metoprolol: 1978

Montelukast: 1998

Morphine: early 1800's

Omeprazole: 1989

Penicillin: 1945

Phenbezamine (first antihistamine): 1942

Prednisone: 1955

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Sertraline: 1990

Spironolactone: 1959

Sulfanilamide (first modern antibiotic): 1935

Tolbutamide (first oral anti-diabetic drug): 1956

Tramadol: 1977 (Germany) 1995 (US)

Trazodone: 1981

Valacyclovir: 1995

Verapamil (first calcium channel blocker): 1964

Warfarin: 1954

Zopiclone (first "Z-drug"): 1986

macgyvermedical

Someone asked for this list in date order, so here it is!

Morphine: early 1800's

Aspirin (first NSAID): 1899

Barbital (first barbiturate): 1903

Insulin: 1923 (though many types of insulins would become available over the next century)

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Calcium Carbonate (TUMS): 1930

Sulfanilamide (first modern antibiotic): 1935

Nitrogen Mustard (first chemotherapy agent): early 1940's

Phenbezamine (first antihistamine): 1942

Penicillin: 1945

Diphenhydramine: 1946

Methotrexate: 1947

Lithium: 1949

Acetaminophen: 1950

Chlorpromazine (first antipsychotic): 1952

Iproniazid (first antidepressant (MAOI)): 1952

Methylphenidate: 1954

Warfarin: 1954

Prednisone: 1955

Tolbutamide (first oral anti-diabetic drug): 1956

Chlorothiazide (first thiazide diuretic): 1957

Metformin: 1957 (France) 1995 (US)

Furosemide: 1959

Hydrochlorothiazide: 1959

Spironolactone: 1959

Imipramine (first tricyclic antidepressant): 1959

Chlordiazepoxide (first benzodiazepine): 1960

Amitriptyline: 1961

Verapamil (first calcium channel blocker): 1964

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Allopurinol: 1966

Albuterol: 1969 (UK) 1982 (US)

Ibuprofen: 1969 (UK) 1974 (US)

Amoxicilin: 1972

Naproxen: 1976 (Rx) 1990 (OTC)

Cyclobenzeprine: 1977

Tramadol: 1977 (Germany) 1995 (US)

Metoprolol: 1978

Captopril (first ACE inhibitor): 1981

Trazodone: 1981

Alprazolam: 1981

Glipizide: 1984

Bupropion: 1985

Buspirone: 1986

Zopiclone (first "Z-drug"): 1986

Lovastatin (first statin): 1987

Azidothymidine (first antiviral): 1987

Lisinopril: 1987

Fluoxetine (first SSRI): 1988

Omeprazole: 1989

Amlodipine: 1990

Sertraline: 1990

Gabapentin: 1993

Losartan (first ARB): 1995

Valacyclovir: 1995

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Montelukast: 1998

Aripiprazole: 2002

Apixiban: 2012

#I would not survive a world without Tylenol and ibuprofen

lady bird is such a perfect movie fr

#still greta’s best idk what to tell ya #ignore me

cinnamonbarbies

Drew Barrymore at the Ever After premiere 1998

#drew barrymore

apatheticfluorescence

some hyper famous artists like Van Gogh transcend overratedness and become underrated because they're so normalized. Like I'll look at a van Gogh and I'm like wait this really is amazing you guys don't get it

headspace-hotel

Shakespeare is like this

insufferablepirate

Every time I see a Van Gogh that’s not one of his better known pieces it absolutely blows me away

Have you seen this shit my liege? smh unreal

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louferrignojrofficial

JONAH + AMY

#superstore

oliviasource

OLIVIA RODRIGO the cure (behind the scenes)

#olivia rodrigo

lakevida

i think its charming when peoples personal lives improve and they get drastically worse at posting

ms-demeanor

How do you feel about driving?

I can drive, I am good at driving, I enjoy driving.

I can drive, I am good at driving, I do not enjoy driving.

I can drive, I am bad at driving, I enjoy driving.

I can drive, I am bad at driving, I do not enjoy driving.

I haven't learned to drive, I think I would enjoy driving.

I haven't learned to drive, I do not think I would enjoy driving.

I can't drive anymore, I was good at it, I enjoyed driving.

I can't drive anymore, I was good at it, I didn't enjoy it.

I can't drive anymore, I was bad at it, I enjoyed it.

I can't drive anymore, I was bad at it, I didn't enjoy it.

Remaining time: 22 hours 31 minutes

#second one #polls

i think i also want to start my journey to get a personal trainer certification… 👩🏻‍🦯

#like obviously i will still be an accountant for the foreseeable future #but why not do something I’d been wanting to do for a while on the side #ignore me

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pitchburgh

good or not, would anyone else WANT your url?

MANY people would want my Tumblr handle

a small handful of folks might want my Tumblr handle

I'm the only one who wants my url (positive)

Honestly? I don't even want this url myself

Voting ended onJun 1

#maybe #polls

sulietsexual

Clark Kent + 😁😁😁 Requested by Anonymous

#smallville

robbiegk

BAD BUNNY Rolling Stone — Eric Rojas (2025)

#benitoooo #bad bunny

sik3rning

squidward cleaning your filthy ass blog

polish-lolita

#new girl

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