This reminds me of the rumors of a female Bateman and American Psycho 2: All American girl.
Hot take: i would like to see a female Patrick Bateman. Not a genderbent per se, but You could 100% adapt American Psycho to a female protagonist.
What makes A.P so good is not only the killings and violence, but the way they're used in a satiric critique to the wealthy yuppie culture, toxic masculinity and Even repressing homosexuality because of societal standards.
Understanding that, i'm sure a female director/writer would be able to tranform that into a questioning to double standards between men and women, internalized misogyny.
But now that i think about it, if we wanted for the female character to stay true to Patrick's, they would need to do something more alike to The Substance.