mindless...

A Nervous Old Man (right) and his Emotional Support Violence Machine (Left)

get a black t-shirt. ideally not a nerdshirt, but band shirts can work

get a pair of black jeans (or shorts, if it's hot out)

paint your nails black

wow, that feels kinda nice actually

put on a little eyeliner

realize how empty you've felt your whole life

maybe try some black eyeshadow

think about using a new, more androgynous name, like Raven or Morgan

start estrogen

Hypnotic suggestions from being mind controlled persist after the controller’s death, causing the victim to occasionally take actions to support the cause of a mind flayer cult that no longer exists.

Repeated demonic possession has left the patient with permanent gaps in their soul’s defenses, causing them to immediately get re-possessed if they go outside a consecrated area.

Post-resurrection trauma as the revived soul remembers an unpleasant afterlife.

Curse of bad luck - makes any small illness or injury potentially fatal if not treated with anti-curse in addition to anti-infection procedures

Magical reliance on a magical or nonmagical substance - can have any number of side effects

Repeatedly being drunk by vampires can cause an increase in blood production and therefore high blood pressure and related ailments. Can be treated by blood letting.

There’s a lot of hybridization happening in a lot of fantasy settings, and that’s just asking for a lot of people with weird half-dragon genetic disorders. Works out fine for some people, not so much for others.

Parasitized by (insert creature here). If you don’t take the correct precautions to keep it dormant it will continue to spread and eventually hatch out/transform you.

Repeated contact with the undead has left you open to their influence - leading to hearing or seeing things that other mortals can’t, which can distort or distract from more mundane concerns.

Alternately to being more vulnerable to intrusion, one’s soul can form a scar that makes helpful magic more difficult to take in.

Sleep disorders that make one fall into an impenetrable sleep at a specific trigger, or to do so for years at a time.

Out of phase with 4D space, one’s body not connected to itself or anchored in place/time in the usual way. There could be a consistent two hour gap between the things you hear and what has happened, you might clip into the floor as if it was in a different place for you, or you might slide through the material plane in cross section.

Intermittent intangibility.

Split into two people, each with only half your traits.