Hrrrrrrrrrrrngh Blake Belladonna and Yang Xiao Long from RWBY. I warn you I'm about to rant like a rabid lunatic and I will be spoiling.
Blake's a ninja catgirl whose incredible compassion lead her to try to see the best in a troubled badboy freedom fighter by the name of Adam Taurus and get lured into a horrifically abusive relationship. She spent years being systematically broken down, retreating into herself until one day his egotistical crusade for vengeance went too far and she cut herself free from him and ran.
Yang's a brawny girl from a family of monster hunters who's mom abandoned her at birth and who's step mom mysteriously vanished on a job one day. Grappling with both deep and dark abandonment issues and the prospect of having to almost singlehandedly raise her little sister Ruby and hold their family unit together as a very very young child, Yang learned to cope by hiding her hurt behind a facade of irreverence and cocky bravado. She got strong because she needed to be a rock for everbody else.
The two of them begin their first year of monster hunting school and would you believe it, they meet and end up forming a team together (along with Ruby and a bitchy rich girl with a heart of gold named Weiss). There's a connection between the two basically immediately.
Yang sees the mysterious, withdrawn yet clearly deeply hurt Blake and being the protective person that she is makes it her mission to help coax her out of her shell. In doing so though, she lets that facade of hers slip a little. In trying to get Blake to lower her walls, she accidentally ends up inviting Blake in, possibly closer than she has anyone before.
Blake for her part after spending so long trapped in an environment of emotional abuse and self loathing is taken aback by Yang's incredible warmth and the sheer kindness and understanding she shows her. Yang has this way of making her feel loved even though she believes herself to be accursed and unlovable. Despite her best efforts to keep emotional distance between herself and everyone around her, she can't help but be endeared to this big, loud, dorky yet caring and sensitive girl.
Things proceed like that for a while, adventures are had, found families are formed, feelings are talked about, there's some low stakes flirting etc. Blake and Yang grow closer and closer and come to rely on each other. Then the worst happens. Everything goes to hell, the school is lost, the comfortable status quo is shattered and in the midst of all this chaos Adam Taurus re-enters the picture. He did not take Blake leaving him well. He promises to make it his mission to destroy everything that she loves. To that end, when Yang does what she always does and throws herself at him to protect Blake, he cuts Yang's arm off.
Afterwards, blaming herself for everything that's transpired and absolutely distraught with guilt, Blake runs away again. The team splits up and the two are separated. That facade that Yang has spent her whole life maintaining has been irrevocably shattered and now she has once again been abandoned, this time by the one person she thought she might actually be able to allow herself to rely on the way everyone relies on her.
They spend a long time apart trying to come to terms with the magnitude of everything that's happened and slowly recovering each in their own way. They pine for each other so hard the entire time and it is AGONY.
The four girls do eventually reunite though and having done a lot of growing and confronting her deadbeat bio mom and getting some bittersweet catharsis on those abandonment issues, Yang does what Adam never could, she forgives Blake for leaving.
It takes time and a little more life or death bonding for the rift between the two of them to mend fully but eventually they're back to a comfortable place and constantly making great big moony eyes at one another all over the place. And now that they're bond is fully reestablished they face down Adam, the shared nemesis who's come between them this whole time and they kill the shit out of him with the power of love.
After a couple more of seasons of them being all over each other given that they are at this point girlfriends in everything but name because while she's come a long way Yang's fear of vulnerability is still too strong for her to take that final step, the universe itself gets tired of waiting and straight up traps the two of them in a pocket dimension where they're dangled over an infinite abyss until they work out their issues.
They are my favorite love story ever told. Nothing compares to them.