Appealing to "Human Nature" is such a comically self-defeating argument for any revolutionary ideology. Like it's a stupid argument no matter what; the idea of human behaviour on both an individual and societal level being primarily the result of innate unchanging characteristics is directly contradicted by everything that social science and economics have taught us for as long as those fields of study existed. But at least, if you accept its premises, this argument works as a defence of the Status Quo. Things are a certain way because humans are a certain way and therefore there's no point trying to change them; this at least follows a consistent logic. Like Capitalism is clearly a product of whatever "human nature" is, because if it wasn't then it would have never been invented and adopted. The rhetorical trick is convincing people that it's the only thing "human nature" could produce and that any alternative systems are "unnatural" rather than obviously being another manifestation of humanity
But for something like Anarchism this argument makes no sense at all. If Anarchism really was the most "natural" system for humans, then why aren't we living under it? Why did any alternate systems develop, let alone succeed and succeed far more than Anarchism ever has, if they're so unnatural? Like as something produced and widely adopted by humans, the social structures we oppose are every bit as "natural" as the ones we support. The only alternative is to say that "The State" or "Hierarchy" or whatever original sin we want to blame all worldly evil on came from beyond humanity. Like were states imposed on us by Alien Infiltrators? Was Hierarchy the invention of some Great Satan that led us all astray? Don't be ridiculous. Whatever "Human Nature" is (if such a thing even meaningfully exists), all of humanity's products both good and bad must definitionally be part of it. It won't do any good to just excise the parts we don't like, and you sound downright ridiculous when your definition of "Human Nature" is directly contradicted by the simple experiences of living in this world as it currently is. It's much better to live by Karl Marx's favourite maxim: Nothing human is alien to me
