#xgeva

Global Xgeva Market is witnessing steady expansion fueled by evolving treatment protocols and increased demand from oncology and bone disorder therapeutics. Market dynamics are shaped by increasing clinical adoption and strategic initiatives by leading market players, driving business growth amid industry challenges. Market Size and Overview Global Xgeva Market is estimated to be valued at USD 2,501.1 Million in 2025 and is expected to reach USD 3,140.7 Million by 2032, exhibiting a compound annual growth rate (CAGR) of 2.7% from 2025 to 2032. 

This Xgeva Market Size reflects growing driven by advancements in bone metastases and oncology care, expanding the market scope. The industry size is projected to benefit from both emerging market segments and increasing awareness among healthcare professionals. The Xgeva market report highlights steady market revenue growth, underpinned by positive market trends and expanding applications across diverse patient populations.

After that, I decided to go to Urgent Care, because I thought I had another UTI. I was/still am in a lot of pain when I go to the bathroom. (It was the worst last night.) One symptom I forgot to mention was that I was bleeding for a few days. Not a good sign.

I made it a point to tell them not to do the pregnancy test. I said I had a radical hysterectomy, so everything in that area’s gone. They asked how long ago it was. As if that mattered. I told them. Then, later they said I was taking birth control. I’m not. The only thing remotely close to that I could think of was the anastrozole. It’s an aromatase inhibitor. Since my cancer is hormone positive, it helps with my hormones. I explained this. I looked later, and there it was…they did the pregnancy test. Now, I’d be even more pissed off if I wasn’t covered. I’d have to pay for a pointless test. It’s like they thought I lied this way, too. They did it without my consent. If the result was anything but negative, something would have been wrong on their end.

Prostate cancer treatments, particularly hormone therapy (ADT) can have a significant effect on speeding up the process of thinning and weakening the bones. There are some available treatments (Zoledronic acid aka Zoladex and denosumab aka Xgeva) which are designed to slow down or reverse this process; however, they are known to have many adverse side effects themselves.  These side effects can include severe fractures of the femur which could limit survival and cataracts.  For this reason, these treatments are usually used later, when men become castrate resistant and metastatic.  

According to results from a phase III trial that was presented at the 2018 ESMO Congress, contrary to previous data, denosumab was shown to decrease the risk of developing fractures without a higher incidence of cataracts in men with non-metastatic prostate cancer. 

In a previous study, low-dose denosumab significantly increased bone mass and reduced vertebral fracture risk. However, unlike other randomized trials that evaluated denosumab, this study showed that this drug resulted in increased development of cataracts in those who received it compared with those who were given a placebo, said Scott T. Tagawa, MD, MS.

Tagawa said, “We wanted to prove if these [earlier] results were real and not just a fluke, so we undertook this newer study.”

In the randomized phase III trial (NCT00925600), men with non-metastatic prostate cancer with bilateral orchiectomy or initiated ADT were randomized 1:1 to receive 60 mg of denosumab every six months or placebo. They found that after 12 months the development or progression of cataracts was similar in the denosumab and placebo arms. They also found that the rates of adverse events leading to treatment discontinuation, and death were similar in the two arms.

Fall allergies while on chemo

Earlier this week I noted there wouldn’t be any real post that day due to not feeling very well and my brain fog being too thick. For the last few days it has been hard to put thoughts together and breathing has been very hard. Luckily today I seem to be back to normal and believe it was in fact fall allergies which took me down for the last few days.

One thing I love about our home is that we…

Got my bone shot today

Every four weeks I have to get a shot to rebuild my bones. This is due to the fact my cancer has spread from my lymphatic system and into my bones, known as bone metastasis. The drug I take is called xgeva, also known as denosumab. In this post I will briefly blog about what xgeva does.

Xgeva (denosumab) is a drug often used to treat osteoporosis and hypercalcemia. Recently it has also been used…