#toxicity

Herbal and dietary supplements (HDS) are widely utilized worldwide as supplementary and alternative medicine modalities that can cause hepatotoxicity. HDS consists of nutrients, minerals, or additional plant materials and substances derived from such plant life. They’re being taken by oral route and intended to augment one’s diet and improve one’s health and properly-being. There’s a bent for false reporting the amount of food they consume through patients and the significance of their utilization is under-recognized by physicians, although no single causality evaluation method is ideal for hepatotoxicity caused by HDS. The most extensively used method is the Roussel Uclaf Causality Assessment Method defining epidemiology, defining an acceptable nomenclature, and identifying culprit ingredients, predisposing host characteristics, and useful biomarkers are all things that need to be addressed for harm must all be priorities in the future. Herbal medicines have long been thought to be safe by people because they’ve been utilized for thousands of years in disease treatment despite potential toxicity, particularly “drug-induced liver injury” (DILI). Despite the risk of side effects, herbal medications have become increasingly popular around the world due to a lack of regulatory oversight.

Vitamin D deficiency is very common among the people of Saudi Arabia. Majority of the population here is aware of it and most of the people try to have medication without checking their vitamin D level or even consulting the doctors, due to Vitamin D related toxicity is very common among the general public. The aim to conduct this cross section survey was to study the awareness of Vitamin D deficiency and toxicity among the population of Saudi Arabia. The cross-sectional study was conducted by developing questionnaire related to the deficiency and the toxicity of vitamin D, The questionnaire was generated in Tabuk city, Saudi Arabia in March, 2022. 400 people participated in the survey out of which were mostly female participants. The education level of the participants was highest among the age of 31-45 and educational qualification was at university level. Results indicated that the general population is well aware of vitamin D deficiency but they had very little knowledge about vitamin D intoxication.