Herbal medicine has become one of the considered alternatives in curing many diseases, including diabetes mellitus. It was found that Insulin Plant (Costus pictus) and Cherry Tree (Muntingia calabura) contain compounds that can help in treating diabetes. This study aims to investigate and compare the anti-diabetic activity of fresh leaf extracts of the Insulin plant and Cherry tree in a diabetes-induced Albino mouse (Mus musculus) at different concentrations. To attain the objectives, researchers utilized and prepared fresh leaf extracts of the Insulin plant and Cherry tree at different concentrations. The blood glucose level of the mice from each setup was tested every after 3 days within 15 days using a glucometer to monitor blood sugar level. After the experimentation, the results showed that as the concentration of the fresh leaf extracts both from the insulin plant and cherry tree increases, the dropping of blood glucose level also increases which indicates that administering higher concentration of the insulin plant and cherry tree fresh leaf extract increases the effectivity in lowering the blood glucose level. From the results, it can be concluded that the Insulin plant and Cherry Tree fresh leaf extract have the promising anti-diabetic property that could be of great help in the field of medicine.











