The Scientific Research Notes of S. Sunkavally. Printed Part. Page 4.
Dates unclear, but certainly between 2006-2012.
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The Scientific Research Notes of S. Sunkavally. Printed Part. Page 4.
Dates unclear, but certainly between 2006-2012.
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The Science Research Notes of S. Sunkavally. Page 224.
Though "poker faces", psoriasis and skin diseases show their last CARD: 1 4 Myc should be enough
Our skin, the body’s largest organ–provides the first line of defense against infections and many other threats to our health. Decades of research has shown that a wide range of diseases can occur, or become worse, when the skin cannot form an effective barrier. Millions of people are affected by eczema, psoriasis and other inflammatory skin disorders. Now, experts in human genetics and asthma…
The MYC gene is a proto-oncogene. A proto-oncogene is a normal gene that becomes altered by mutation and helps contribute to cancer formation.
If someone were to draw a similar map of relationships among genes in a normal human cell, then proto-oncogenes and tumor suppressors such as ras, myc, neu and Rb would sit at the hub of this cellular city, radiating webs of colored strings in every direction. Proto-oncogenes and tumor suppressors are the molecular pivots of the cell. They are the gatekeepers of cell division, and the division of cells is so central to our physiology that genes and pathways that coordinate this process intersect with nearly every other aspect of our biology. In the laboratory, we call this the six degrees of separation from cancer rule: you can ask any biological question, no matter how seemingly distant--what makes the heart fail, or why worms age, or even how birds learn songs--and you will end up, in fewer than six genetic steps connecting with a proto-oncogene or tumor suppressor.
The Emperor of All Maladies by Siddhartha Mukherjee
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