Mar 29
Clostridioides difficile-Derived Extracellular Vesicles Induce Proinflammatory Responses in Macrophages - Research
Clostridioides difficile (CD) is a leading cause of antibiotic-associated diarrhoea in both hospitalized and non-hospitalized patients. This study explores the role of extracellular vesicles (EVs) derived from Clostridioides difficile strain 630 (CD630-EVs), which released spherical EVs during in vitro culture, in modulating pro-inflammatory cytokine production in macrophages. Proteomic analysis…
#animals#Clostridioides#Clostridioides difficile* / metabolism#Cytokines / metabolism#difficileDerived#doi:10.1002/jev2.70251#extracellular#Extracellular Vesicles* / immunology#Extracellular Vesicles* / metabolism#Fangfang Fan#humans#Inbred C57BL#induce#Inflammation* / metabolism#Macrophages#Macrophages* / immunology#Macrophages* / metabolism#MEDLINE#Mice#National Center for Biotechnology Information#National Institutes of Health#National Library of Medicine#NCBI#NIH#NLM#pmid:41904635#proinflammatory#Proteomics#PubMed Abstract#RAW 264.7 Cells
