#dendritic cells

Propaganda!

The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. Part of the endomembrane system in the cytoplasm, it packages proteins into membrane-bound vesicles inside the cell before the vesicles are sent to their destination. It resides at the intersection of the secretory, lysosomal, and endocytic pathways. It is of particular importance in processing proteins for secretion, containing a set of glycosylation enzymes that attach various sugar monomers to proteins as the proteins move through the apparatus.

Anti-cancer Courier

A virus-like particle engineered to deliver cancer-specific antigens [molecule, complex or fragment with potential trigger an immune response] to dendritic cells of the immune system which will in turn activate an attack by T cells on the tumour

Read the published research article here

Image from work by Ruijing Tang and colleagues

The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, China

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in eLife (reviewed preprint), June 2024

Cells At Work!

Opening - "Mission! Ken - Ko - Dai - Ichi" by Kana Hanazawa, Tomoaki Maeno, Daisuke Ono and Kikuko Inoue

Rockefeller University and the Rockefellers. They’re not a new band but a group of some of the most influential figures in scientific discovery in the medicinal field; all of whom graduated from or researched at Rockefeller University. Rockefeller University is renowned for having an astounding 24 Nobel laureates amongst its alumni.

The most recent addition to Rockefeller’s long list of Nobel laureates was Ralph M. Steinman who discovered dendritic cells and their role in immunology. Steinman, sadly, died three days prior to being awarded the Nobel in 2011. Surprisingly the Nobel Foundation, who has rules against post humous recognition, was unaware of Steinman’s death at the time and Claudia Steinman received the award from King Carl XVI Gustaf of Sweden on her husband’s behalf.