Top Posts Tagged with #dc2a

Transcription factors TCF4 and KLF4 respectively control the development of the DC2A and DC2B lineages - New Study

Nature Immunology, Published online: 23 July 2025; doi:10.1038/s41590-025-02208-5 Here Zhu et al. investigate the ontogeny of type 2 dendritic cells (DC2s) in mice. Using Klf4 expression to distinguish conventional DC precursors from plasmacytoid DCs, they identify two pre-DC2 populations with their development controlled by TCF4 and KLF4 that give rise to DC2A and DC2B cells. Summary Zhu et al.…

#Biomedicine #Cellular immunity #control #Conventional dendritic cells #DC2A #DC2B #Development #factors #general #immunology #Infectious diseases #KLF4 #lineages #Study #TCF4 #transcription

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