Consort of the Queen of the Mithra

My guesses would be:

Kurozumi Orochi talking like the Yes Guy from The Simpsons

Rosward talking like Funky Kong

Kaido talking like Macho Man Randy Savage

Boa Hancock's sisters talking like snakes

Doflamingo talking like Johnny Bravo in a high-pitched voice

Brook talking like Rick James

Jaygarcia Saturn talking like a Jewish rabbi

Baby 5 speaking in baby talk (with a poorly-edited-in bib added to cover her cleavage)

Pappag talking like Patrick Star with a Jamaican accent

Bartholomew Kuma talking like Bart Simpson

Sakazuki talking like M. Bison from that Street Fighter 2 cartoon

Kaku sounding like Normal Spongebob

Capone Bege talking like the Donbot from Futurama

Carrot talking like Bugs Bunny

Giants saying Fee-fi-fo-fum all the time and speaking in Swedish accents

Dr. Hogback talking like Peter Lorre's version of Igor

Gecko Moriah talking like Dracula (maybe even the Sesame Street version)

Here's an idea I saw someone post on a YouTube comment section for Jinbe: Talking like Mr. Miyagi

Gol D. Roger suddenly talking like Wario after many episodes with a different voice

Figarland Shamrock talking in an Irish accent

Donquixote Rosinante talking like the Joker or Buggy the Clown

Gladius talking like Rick Sanchez (including burping a lot)

Franky talking like the Terminator

A Fishman talking like that crab from Little Mermaid

Namur talking like Buford from Phineas and Ferb

Batman talking like... the other Batman

Queen talking like Eggman with a lisp

Pekoms talking in Disco slang

Wanda talking like Wanda from The Fairly OddParents

Vander Decken talking like the Flying Dutchman

Yasu the Hedgehog talking like Sonic

Rocks D. Xebec talking like a rock star

Dr. Vegapunk talking like Mario

Jabra talking like Dick Dastardly

Imu talking like Emperor Palpatine

Ragnir talking like Alvin and the Chipmunks

Here is an AI-generated picture of two Drauks from Ever Oasis (names are Alana and Um) making out with each other.

Here's an AI-generated picture of a Shroob abortionist.

Here's an AI-generated picture of a female Mithra from Final Fantasy 11, but much buffer.

First, here's an article on what the Harpeia are: https://ffxiclopedia.fandom.com/wiki/Category:Harpeia

Here is a pic of a Pandaren woman with clear signs of diabetes.

And yes, this is a diabetic fat joke.

In the first game, Gruntilda was obsessed with becoming beautiful, to the point of kidnapping a prettier girl (Tootie) and stealing her beauty, wronging someone. That causes her to become buried under a rock long enough to be reduced to an undead skeleton.

That's when Grunty stops caring about being beautiful and only cares about restoring her flesh. But she's still willing to wrong others for that goal, by sucking the life force out of other people and creatures and the environment. That ends up with her body being destroyed and reduced to a decapitated skull.

But when Grunty met Banjo-Kazooie again, they also meet LOG, who gives Grunty a new biomechanical robot body for her skull, being satisfied with it and not caring about her looks at all anymore. While Grunty predicted that she'd end up as an eyeball or brain by the end of Nuts and Bolts, that didn't happen. Because she didn't wrong anybody for the purpose of getting that new body, and seems grateful for it, she instead ends up as a slave in LOG's video game factory, while keeping her new body.