my weird aunt vriska who has the best games at summer camp
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my weird aunt vriska who has the best games at summer camp

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When Drugs Became Available
Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:
Acetaminophen: 1950
Albuterol: 1969 (UK) 1982 (US)
Allopurinol: 1966
Alprazolam: 1981
Amitriptyline: 1961
Amlodipine: 1990
Amoxicilin: 1972
Amphetamine/Dextroamphetamine (together as Adderall): 1996
Apixiban: 2012
Aripiprazole: 2002
Aspirin (first NSAID): 1899
Azidothymidine (first antiviral): 1987
Barbital (first barbiturate): 1903
Bupropion: 1985
Buspirone: 1986
Calcium Carbonate (TUMS): 1930
Captopril (first ACE inhibitor): 1981
Chlordiazepoxide (first benzodiazepine): 1960
Chlorothiazide (first thiazide diuretic): 1957
Chlorpromazine (first antipsychotic): 1952
Cyclobenzeprine: 1977
Diphenhydramine: 1946
Furosemide: 1959
Fluoxetine (first SSRI): 1988
Gabapentin: 1993
Glipizide: 1984
Hydrochlorothiazide: 1959
Ibuprofen: 1969 (UK) 1974 (US)
Insulin: 1923 (though many types of insulins would become available over the next century)
Imipramine (first tricyclic antidepressant): 1959
Iproniazid (first antidepressant (MAOI)): 1952
Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
Lisinopril: 1987
Lithium: 1949
Losartan (first ARB): 1995
Lovastatin (first statin): 1987
Naproxen: 1976 (Rx) 1990 (OTC)
Nitrogen Mustard (first chemotherapy agent): early 1940's
Methotrexate: 1947
Methylphenidate: 1954
Metformin: 1957 (France) 1995 (US)
Metoprolol: 1978
Montelukast: 1998
Morphine: early 1800's
Omeprazole: 1989
Penicillin: 1945
Phenbezamine (first antihistamine): 1942
Prednisone: 1955
Propranolol (first beta blocker): 1965 (UK) 1967 (US)
Sertraline: 1990
Spironolactone: 1959
Sulfanilamide (first modern antibiotic): 1935
Tolbutamide (first oral anti-diabetic drug): 1956
Tramadol: 1977 (Germany) 1995 (US)
Trazodone: 1981
Valacyclovir: 1995
Verapamil (first calcium channel blocker): 1964
Warfarin: 1954
Zopiclone (first "Z-drug"): 1986
Someone asked for this list in date order, so here it is!
Morphine: early 1800's
Aspirin (first NSAID): 1899
Barbital (first barbiturate): 1903
Insulin: 1923 (though many types of insulins would become available over the next century)
Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)
Calcium Carbonate (TUMS): 1930
Sulfanilamide (first modern antibiotic): 1935
Nitrogen Mustard (first chemotherapy agent): early 1940's
Phenbezamine (first antihistamine): 1942
Penicillin: 1945
Diphenhydramine: 1946
Methotrexate: 1947
Lithium: 1949
Acetaminophen: 1950
Chlorpromazine (first antipsychotic): 1952
Iproniazid (first antidepressant (MAOI)): 1952
Methylphenidate: 1954
Warfarin: 1954
Prednisone: 1955
Tolbutamide (first oral anti-diabetic drug): 1956
Chlorothiazide (first thiazide diuretic): 1957
Metformin: 1957 (France) 1995 (US)
Furosemide: 1959
Hydrochlorothiazide: 1959
Spironolactone: 1959
Imipramine (first tricyclic antidepressant): 1959
Chlordiazepoxide (first benzodiazepine): 1960
Amitriptyline: 1961
Verapamil (first calcium channel blocker): 1964
Propranolol (first beta blocker): 1965 (UK) 1967 (US)
Allopurinol: 1966
Albuterol: 1969 (UK) 1982 (US)
Ibuprofen: 1969 (UK) 1974 (US)
Amoxicilin: 1972
Naproxen: 1976 (Rx) 1990 (OTC)
Cyclobenzeprine: 1977
Tramadol: 1977 (Germany) 1995 (US)
Metoprolol: 1978
Captopril (first ACE inhibitor): 1981
Trazodone: 1981
Alprazolam: 1981
Glipizide: 1984
Bupropion: 1985
Buspirone: 1986
Zopiclone (first "Z-drug"): 1986
Lovastatin (first statin): 1987
Azidothymidine (first antiviral): 1987
Lisinopril: 1987
Fluoxetine (first SSRI): 1988
Omeprazole: 1989
Amlodipine: 1990
Sertraline: 1990
Gabapentin: 1993
Losartan (first ARB): 1995
Valacyclovir: 1995
Amphetamine/Dextroamphetamine (together as Adderall): 1996
Montelukast: 1998
Aripiprazole: 2002
Apixiban: 2012
Being able to draw older people as attractive without reducing or erasing the visual signs of aging, and in fact showing that they're attractive because of those signs, is an artistic skill that should be valued so much more. Honestly, it should earn you an immediate fortune because holy fuck is it a rare commodity. There are so many artists who seem to think attractiveness and aging exist in opposition to each other, so they smooth every wrinkle, erase every crease, and de-age the character until they're basically thirty with silver hair. But when an artist can look at crow's feet, smile lines, weathered skin, deep-set wrinkles, and all the little traces of a life well lived and say, "No, that's what makes them beautiful," that's a level of artistic observation and care I wish we celebrated more often.
If Funko Pops weren't evil enough they once shut down itch.io for a little bit

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
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Alright since a lot of ppl seem really confused I wanted to answer a question I saw in the tags
....hi 👋
how it feels to stop tossing and turning and get up to piss
VIETNAM HAS MOSS FROGS.
THEY LIVE IN MOSS.
THEY ARE CUTE AS FUCK!
Thank you for coming to my ted talk. Now lets go live the way of the moss frog.
they had an understanding of asmr back in hunter gatherer days and there was always somebody who's job it was to whisper at bedtime and tap their acrylic nails on a mammoth bone or something
this was lost from our human knowledge due to pompeii

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
Free to watch • No registration required • HD streaming
:( please dont do this to me man
Whatever youtube equivalent throne has must be crazy
yeah I don't have anything funny to say about this update this shit bangs so hard

Anya is live and ready to show you everything. Watch her strip, dance, and perform exclusive shows just for you. Interact in real-time and make your fantasies come true.
Free to watch • No registration required • HD streaming
This blog is literally the biggest cry for help
shut up i’ll fuck your dad