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From Wikipedia:

Nuestra Señora de la Santa Muerte (Spanish for Our Lady of Holy Death), often shortened to Santa Muerte, is a female deity or folk saint in Mexican and Mexican-American folk Catholicism. A personification of death, she is associated with healing, protection, and safe delivery to the afterlife by her devotees. Despite condemnation by the Catholic Church, her cult has become increasingly prominent since the 2000s.

The worship of Santa Muerte is condemned by the Catholic Church in Mexico as invalid, but it is increasingly firmly entrenched in Mexican culture.

Santa Muerte is also seen as a protector of homosexual, bisexual, and transgender communities in Mexico, since many are considered to be outcast from society. Many LGBT people ask her for protection from violence, hatred, disease, and to help them in their search for love.

Her intercession is commonly invoked in same-sex marriage ceremonies performed in Mexico. The Iglesia Católica Tradicional México-Estados Unidos, also known as the Church of Santa Muerte, recognizes gay marriage and performs religious wedding ceremonies for homosexual couples.