superwoman yeah!

Kanker Payudara : Epidemiologi dan Faktor Risiko

Dirangkum dari jurnal ilmiah: Harbeck et al. (2019) in Nature Reviews

EPIDEMIOLOGI

Di tahun 2018 : 2.1 juta kasus baru kanker payudara (pada wanita); 626.679 kematian akibat kanker payudara

Insidensi di tingkat global:

Insidensi tinggi di negara maju

Insidensi rendah di negara berkembang

Fenomena insidensi rendah di negara berkembang ini berhubungan deteksi dini yang belum se-maju di negara…

It was 20.10 when I left the dark room in the 2nd floor of my lab building. I had just got my western blot result; a result that put a big smile in my face. I couldn’t wait to show the result to my Sensei (professor in Japan), but I didn’t think he’s still in the lab at those time. Turned out, I bumped into him in the lab corridor.

“Have you done the western blot?” Ah! He remembered that I’ll…

A trip to Alps village: Wengen

This summer, we are lucky to have our parents and brother visiting us in Swiss. My mom has always wanted to see the Alps ever since she watched the Sound of Music. So, we planned our trip to interlaken and Jungfrau region to breathe the air of the Swiss Alps. Our choice to stay was Wengen, a car-free village in the middle of mountaneous Jungfrau.

After a half-day sightseeing in Bern, we took…

It’s been a month since our trip to Istanbul; however, the charm of this metropolitant city still slip in my mind. How could we don’t fall in love with the only city stretched across two continents? How could we don’t fall in love with the city where some big empires rule the world for millenias? It feels like every inch of the city tells us about the glory of the past. I really wish I could come…

With an area of 160km2, Liechtenstein is one of the smallest country on earth (it is even only about a third of Sleman, my hometown in Indonesia). Being a neighbour of Swiss, we don’t want to miss a chance to visit this mini country during our time here. Hence, we planned an unambitiousdaytrip from Geneva to Vaduz, the capital of Liechtenstein. It took 4.5 hours trip by train and bus. Luckily as…

In the footsteps of the Prophet [Book review]

All muslim might know and memorize the main events in the life story of Prophet Muhammad (PBUH): who are his parents; that he faces difficulty even before he was born (with the death of his father) and later lose his beloved family for many times; that he was a trustworthy and noble man in Mecca; that he got the revelation at his 40 and encounter cruelty while spreading the divine message,…

Digital Minimalism [Book Review]

After being influenced by the ‘Deep Work’ ethos, I was excited knowing Cal Newport would soon release another book highlighting the complicated relationship of productivity and technology. Didn’t think twice, I pre-ordered this ‘Digital Minimalism’ and it arrived early this February.

The main theses of this book are: (1) how to ‘cut’ your dependence on disruptivetechnology (esp. social media)

Keep​ing up with the reading list

I’ve just started my PhD journey this February. As other new students might feel, I’m excited yet nervous at the same time: will I survive? is this the best lab for me? what would I be after this journey? I’m also nervous as it’s almost 2 years since I left formal school. But, here I am trying to prepare this journey as best as I can.

One thing I try to prepare is how to keep track of my…

Modifikasi post-translasional dan sekresi protein Wnt

Protein Wnt memiliki proses modifikasi post-translasional yang cukup rumit dan memerlukan berbagai protein spesifik, sebelum akhirnya disekresikan dari suatu sel. Oleh karena itu, protein Wnt dengan kemurnian dan aktivitas biologis yang tinggi masih sulit untuk diproduksi hingga saat ini. Berikut adalah alur modifikasi post-translasional dan sekresi protein Wnt dari suatu sel.

Terjadi…

1.Library dengan target biologis tertentu

Contoh: target kinase, GPCR, central nerve system/CNS (senyawa didesain untuk dapat menembus sawar darah otak/blood brain barrier)

2. Koleksi senyawa obat yang telah diketahui aktivitas farmakologinya

Senyawa-senyawa tersebut kemudian dieksplorasi kembali untuk menemukan aktivitas farmakologi lain. Contoh: obat anti-fungal ternyata memiliki…

Menggunakan ‘chemical library’ dalam pengembangan obat dengan high throughput screening (HTS)

Chemical library: koleksi berbagai senyawa yang utamanya digunakan dalam high throughput screeningatau industri manufaktur.

High throughput screening: eksperimen saintifik menggunakan berbagai uji yang secara cepat dapat mengidentifikasi senyawa, antibodi, atau gen yang memodulasi suatu jalur sinyal transduksi.

Hal-hal yang perlu dipertimbangkan dalam memilih komposisi library:

biaya

mana…

Deep Work [Book Review]

I should say that this book is my gem in 2018. I read this book in early 2018, tried to practice some of the rules, and re-read again this one. So, I really think I should try to summarize this book for myself.

Before 2018, I found myself so difficult to focus on a task for a long time (throughout 30 minutes, I check my phone or wandering the internet while trying to finish a task).  Even,…

Entrance Fee: CHF 24,-

Address: Seestrasse 27, 8002 Zürich

My husband plays football, while I was a fan of Germany football team (‘was’ lol, not really watching football nowadays). Hence, we did not miss the chance to visit the FIFA museum during our recent trip in Zurich. Despite a quite high entrance fee, this museum is a BOOM! It is worth every penny if you enjoy football.

The museum…

Favourite place so far in Swiss: Lauterbrunnen. It’s like a piece of heaven on earth. So calm, serene, and of course beautiful!

“This world is getting worse and worse. We should live like we were in the past. Where we live side by side with nature. When everything is so peaceful without nuclear power, terrorist threats, or climate change,” that’s how a lot of people thinking about the world nowadays. Even me, I love to imagine ‘the good old days’ of my childhood. But, is it true that our world getting worse?

Hans Rosling…

Address: Kramgasse 49, 3011 Bern

While strolling in Bern, I did not miss the opportunity to visit the house of one of world’s legend: Albert Einstein. Albert Einstein started his ‘professional’ academic life in Bern. In a house located in the Bern’s old town, the renowned “Relativity Theory” was born. S

The house itself is not really big. It is a 3-rooms apartment in Swiss standard, located on the 2nd floor of Kramgasse No. 49. Inside, there are pieces of furniture that used by Einstein and his family while living in the house. There are also some pieces of journals, papers, and research equipment owned by Einstein. Several texts and pictures depict Einstein’s biography.

Overall, this is a really nice place to visit while in Bern, that could be enjoyed by sparing time ~30 minutes. The location is also central and easily accessed from Bern main station.

facade of Einstein’s house

EInstein with his 1st wife

Yesterday, I had a chance to stroll around Bern for a while. In this autumn, Bern is really breathtaking! Here are some of my snapshots on Bern’s autumn. Anyway, my favorite place is Rose Garden, which offers a pretty view of Bern old town and surroundings.

  Bern parliamentary building faces Aare river

  autumn alley

old town Bern from Rose Garden

view from Rose Garden

another view from Rose…